| Week 1 | Tennessee Titans vs. New Orleans Saints | Sunday, September 10th, 2023 at 1:00pm ET |
| Week 2 | New Orleans Saints vs. Carolina Panthers | Monday, September 18th, 2023 at 7:15pm ET |
| Week 3 | New Orleans Saints vs. Green Bay Packers | Sunday, September 24th, 2023 at 1:00pm ET |
| Week 4 | Tampa Bay Buccaneers vs. New Orleans Saints | Sunday, October 1st, 2023 at 1:00pm ET |
| Week 5 | New Orleans Saints vs. New England Patriots | Sunday, October 8th, 2023 at 1:00pm ET |
| Week 6 | New Orleans Saints vs. Houston Texans | Sunday, October 15th, 2023 at 1:00pm ET |
| Week 7 | Jacksonville Jaguars vs. New Orleans Saints | Thursday, October 19th, 2023 at 8:15pm ET |
| Week 8 | New Orleans Saints vs. Indianapolis Colts | Sunday, October 29th, 2023 at 1:00pm ET |
| Week 9 | Chicago Bears vs. New Orleans Saints | Sunday, November 5th, 2023 at 1:00pm ET |
| Week 10 | New Orleans Saints vs. Minnesota Vikings | Sunday, November 12th, 2023 at 1:00pm ET |
| Week 11 | Bye Week | |
| Week 12 | New Orleans Saints vs. Atlanta Falcons | Sunday, November 26th, 2023 at 1:00pm ET |
| Week 13 | Detroit Lions vs. New Orleans Saints | Sunday, December 3rd, 2023 at 1:00pm ET |
| Week 14 | Carolina Panthers vs. New Orleans Saints | Sunday, December 10th, 2023 at 1:00pm ET |
| Week 15 | New York Giants vs. New Orleans Saints | Sunday, December 17th, 2023 at 1:00pm ET |
| Week 16 | New Orleans Saints vs. Los Angeles Rams | Thursday, December 21st, 2023 at 8:15pm ET |
| Week 17 | New Orleans Saints vs. Tampa Bay Buccaneers | Sunday, December 31st, 2023 at 1:00pm ET |
| Week 18 | Atlanta Falcons vs. New Orleans Saints | Sunday, January 7th, 2024 at 1:00pm ET |
