Josh Shepardson | Wed, May 27th 2026, 5:27am EDT

MLB DFS Picks & Underdog Player Props: Wednesday (5/27)

Wednesday’s MLB DFS main slate at DraftKings and FanDuel starts at 6:35 p.m. ET, and it features nine games at the former and eight at the latter. FanDuel excludes the night’s final game. The Underdog pick’em selections are from the nine games.

Wednesday’s Top MLB DFS Picks & Player Props

Wednesday’s Starting Pitcher Rankings (5/27)

Shohei Ohtani (SP – LAD) vs. Colorado Rockies

Shohei Ohtani has dominated this season. According to FanGraphs, among 128 pitchers with at least 40 innings, Ohtani is first in ERA (0.73), second in xERA (2.39), 18th in xFIP (3.09), 15th in SIERA (3.03), third in WHIP (0.84) and 10th in strikeout rate (28.4%). Ohtani also has four wins and seven quality starts in eight starts spanning 49 innings.

Ohtani has a cupcake matchup to feast on tonight. The Rockies are tied for 28th in wRC+ (85) with a 22.9% strikeout rate versus righties and 26th in wRC+ (87) with a 25.9% strikeout rate on the road in 2026.

Colorado is also 30th in wRC+ (61) with a 28.2% strikeout rate in the previous 30 days. Unsurprisingly, the Dodgers are massive favorites (-420), and the game’s total is eight runs.

Casey Mize (SP – DET) vs. Los Angeles Angels

Among tonight’s probable starting pitchers, Casey Mize is sixth in ERA (2.47), fourth in xERA (2.69), fifth in xFIP (3.74), fourth in SIERA (3.53), fourth in WHIP (0.98) and fourth in strikeout rate (25.1%).

Two of the pitchers ahead of him in ERA and xERA are Gerrit Cole and Jonah Tong, who have made one start and one bulk relief appearance, respectively.

Mize can keep rolling in a plus-matchup tonight. The Angels are tied for 26th in wRC+ (91) with a 25.9% strikeout rate versus righties and third in wRC+ (115) with a 24.5% strikeout rate on the road this season.

Los Angeles ranks 29th in wRC+ (76) with a 31% strikeout rate in the previous 30 days. Finally, the Tigers are -125 favorites, and the game’s total is a pitcher-friendly 7.5 runs.

Steven Matz (SP – TB) at Baltimore Orioles

Steven Matz is overachieving, but he’s pitching OK this year:

4 wins
3 quality starts
3.70 ERA
4.44 xERA
4.25 xFIP
4.37 SIERA
1.11 WHIP
9% walk rate
19.9% strikeout rate
10.2% SwStr%
26.2% CSW%
98 stuff+
104 location+
100 pitching+

Matz’s matchup has pluses and minuses. The Orioles are tied for 21st in wRC+ (87) with a 25% strikeout rate versus lefties, but they’re tied for eighth in wRC+ (109) with a 22.9% strikeout rate at home this year.

Baltimore is also 26th in wRC+ (85) with a 28.1% strikeout rate in the previous 30 days. The Rays are slight favorites (-115), and the game’s total is nine runs. Matz is an intriguing SP2 in GPPs on DraftKings.

Suggested Lineup Stacks

Home (UNIQLO Field at Dodger Stadium)
Game Total/Moneyline: 8.0/LAD -420

Tomoyuki Sugano‘s 3.86 ERA in 10 starts simply isn’t legitimate. His 7.39 xERA is the highest among pitchers with at least 50 innings, and his 4.86 xFIP and 5.03 SIERA are also ugly.

Sugano has yielded a .355 wOBA to lefties and a .322 wOBA to righties since last season. In addition, the Rockies have a below-average bullpen. This is a DraftKings-specific punt, as this game isn’t on FanDuel’s main slate.

Road (Oriole Park at Camden Yards)
Game Total/Moneyline: 9.0 Runs/TB -115

The Rays have a desirable matchup tonight. Trey Gibson is expected to get the ball for the Orioles. In 15 career starts and 61 innings at the Triple-A level since last season, he’s been roughed up for a 5.75 ERA, 4.72 FIP and 1.74 WHIP.

Gibson also has a 5.40 ERA, 6.09 xERA, 5.10 xFIP, 5.02 SIERA and 1.50 WHIP in two appearances (one start), totaling 6.2 innings for the Orioles this season. Baltimore also has a bottom-10 bullpen in ERA this year.

Core Studs

Andy Pages has belted 12 bombs with 33 runs, 49 RBI, seven stolen bases, a .348 on-base percentage (OBP), .235 ISO, .383 wOBA and 147 wRC+ in 224 plate appearances this season.
Junior Caminero has hit 48 homers with a .313 OBP, .254 ISO, .352 wOBA and 128 wRC+ in 772 plate appearances against righties since 2024.
Jonathan Aranda has drilled 27 dongs with a .372 OBP, .213 ISO, .377 wOBA and 144 wRC+ in 608 plate appearances against righties since 2024.

Value Plays/Punts

Richie Palacios has hit seven homers with a .358 OBP, .102 ISO, .318 wOBA and 108 wRC+ in 412 plate appearances against righties since 2024. He also adds speed to the mix, stealing seven bases this season.
Chandler Simpson has a .334 OBP, .309 wOBA and 96 wRC+ in 473 plate appearances against righties since 2024. However, he gets a bump from hitting atop Tampa Bay’s lineup and swiping 14 bases this season.
Ha-Seong Kim is a viable punt at nearly the minimum salary on DraftKings and less appealing on FanDuel. The veteran shortstop has a .333 OBP, .304 wOBA and 96 wRC+ in 211 plate appearances against southpaws since 2024.

Wednesday’s Top 3 Underdog Player Props

Check out our best picks on the MLB Underdog Cheat Sheet

Brandon Lowe (2B – PIT): 1.5 Hits + Runs + RBIs — Higher (0.87x Payout)

Brandon Lowe is raking for the Pirates. In 216 plate appearances, he has recorded 51 hits, including 13 homers, with 32 runs, 33 RBI, a .270 batting average, .356 OBP, .280 ISO, .394 wOBA and 152 wRC+.

Bubba Chandler (SP – PIT): 15.5 Outs — Lower (0.77x Payout)

Bubba Chandler has gone six straight games with fewer than 15.5 outs recorded. He recorded 16 and 18 outs in back-to-back starts on April 12th and April 17th, respectively, but those were the only times he surpassed 15.5 outs this season.

Jameson Taillon (SP – CHC): 2.5 Earned Runs — Higher (0.88x Payout)

Jameson Taillon has been unimpressive on the road. In 99 innings on the road since last season, he has a 4.73 ERA, 4.91 xFIP and 1.17 WHIP. Taillon has allowed over 2.5 earned runs in back-to-back starts and in four out of five road tilts this year.

Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.

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