Jesus Luzardo took the loss Friday, allowing five runs (all earned) on eight hits over 5.0 innings with eight strikeouts and one walk.
Houston got to Luzardo in the third inning. After walking Jose Altuve to open up the inning, Michael Brantley smashed a double to right field before Alex Bregman hit a three-run home run to give Houston the lead. They got to him again in the fourth inning with a leadoff home run from Yuli Gurriel before Brantley hit another double later in the inning that scored Altuve. Luzardo will look to bounce back against the Dodgers at home on April 7.