Chargers running back Kalen Ballage, listed as questionable for Sunday with calf and ankle injuries, is not expected to play vs. the Bills, according to ESPN NFL insider Adam Schefter. (Adam Schefter on Twitter)
With Ballage out, the Chargers are expected to have Austin Ekeler, Troymaine Pope, and Josh Kelley active. Ekeler hasn't played in an NFL game since Week 4 and is unlikely to see his usual workload even if he is able to play on Sunday. That leaves Kelley and Pope as the primary ball-carriers, with Kelley having a slight edge in potential usage.