Dolphins WR Jakeem Grant (ankle) suffered a high-ankle sprain during the team's 26-25 win over the Raiders in Week 16 and has been ruled out against the Bills in Week 17. (Ian Rapoport on Twitter)
Grant's absence in an upcoming critical must-win game against a talented team like the Bills is a significant loss. The Dolphins are dealing with numerous injuries at the wide receiver position, which includes DeVante Parker and Preston Williams on Injured Reserve. Grant could join Williams on IR, leaving fantasy managers with risky streaming options in Mack Hollins, Lynn Bowden Jr. and Isaiah Ford. Bowden Jr. disappointed in Week 16 seeing just three targets but has seen 19 targets over the last three games, making him the best risky investment against an improved Buffalo defense.