Howard exited the Week 11 win over the New Orleans Saints early with a knee sprain and did not return. He was unable to practice this week, and the Eagles ultimately ruled him out. Miles Sanders and Boston Scott will lead the Eagles backfield against the Giants while Howard is out. Sanders is a low-end RB2 and 18th among all running backs in the latest FantasyPros expert consensus rankings. Howard's next chance to return will be Week 13 versus the New York Jets.