Brandon Aiyuk Week 13 Outlook - Bills at 49ers

By Mike Tagliere (FantasyPros), Thu, Dec 3rd 2020, 10:50am EST

The 49ers should get Aiyuk back to the lineup this week, though it's important to monitor the situation throughout the week. The last three times we saw Aiyuk on the field, he was torching defenses for at least six catches and 75 yards in each game, including a touchdown in two of them. He also saw 24 targets over the last two games, but there's an important detail that cannot be ignored in there, and it's that Deebo Samuel was out for both those games. Samuel hasn't seen more than seven targets in any game Samuel has played in, so keep that in mind when setting expectations. The Bills have allowed the 10th-fewest fantasy points per game to wide receivers this year, a number that's been going down as the weeks go on. Last week, we saw them hold the duo of Keenan Allen and Mike Williams to just seven receptions, 66 yards, and one touchdown on 15 targets. There's also the possibility of Tre'Davious White shadowing Aiyuk considering how much Samuel moves around, though they could just choose to play sides. Whatever the case, it hurst Aiyuk's projection that he doesn't go into the slot more than 20 percent of the time, as that's where they've struggled the most. With Samuel back in the lineup, Aiyuk moves back into the high-end WR4 territory.