Byron Buxton should have a good MLB career, but he isn’t our top fantasy prospect
Yesterday I wrote a primer explaining my ranking methodology. If you want to understand why there are foreign players on this list, amateurs, 450+ prospects, and strange ranking placements, please click here . The column for ETA is a prediction of which season each player will lose their MLB rookie status. Next week I will break down 15 hitters and 15 pitchers that I expect to rise up the list considerably for 2016.
Thanks for reading. I hope this helps you in your deep league drafts.
| Rank | Name | Position | Pos Rk | Team/Status | Tm Rk | Age | ETA |
| 1 | Lucas Giolito | RHP | 1 | Nationals | 1 | 21 | 2016 |
| 2 | Tyler Glasnow | RHP | 2 | Pirates | 1 | 22 | 2016 |
| 3 | Corey Seager | SS | 1 | Dodgers | 1 | 21 | 2016 |
| 4 | Julio Urias | LHP | 1 | Dodgers | 2 | 19 | 2017 |
| 5 | Byron Buxton | OF | 1 | Twins | 1 | 22 | 2016 |
| 6 | J.P. Crawford | SS | 2 | Phillies | 1 | 21 | 2017 |
| 7 | Joey Gallo | 3B | 1 | Rangers | 1 | 22 | 2016 |
| 8 | Alex Reyes | RHP | 3 | Cardinals | 1 | 21 | 2017 |
| 9 | Sean Newcomb | LHP | 2 | Braves | 1 | 22 | 2017 |
| 10 | Shohei Otani | RHP | 4 | (Japan) | 1 | 21 | 2018 |
| 11 | Jose De Leon | RHP | 5 | Dodgers | 3 | 23 | 2017 |
| 12 | Yoan Moncada | 2B | 1 | Red Sox | 1 | 20 | 2018 |
| 13 | Brendan Rodgers | SS | 3 | Rockies | 1 | 19 | 2018 |
| 14 | Gleybar Torres | SS | 4 | Cubs | 1 | 19 | 2019 |
| 15 | Blake Snell | LHP | 3 | Rays | 1 | 23 | 2016 |
| 16 | Jose Berrios | RHP | 6 | Twins | 2 | 21 | 2017 |
| 17 | Rafael Devers | 3B | 2 | Red Sox | 2 | 19 | 2019 |
| 18 | Trea Turner | SS | 5 | Nationals | 2 | 22 | 2016 |
| 19 | David Dahl | OF | 2 | Rockies | 2 | 21 | 2017 |
| 20 | Anderson Espinoza | RHP | 7 | Red Sox | 3 | 17 | 2020 |
| 21 | Dansby Swanson | SS | 6 | Braves | 2 | 21 | 2017 |
| 22 | Steven Matz | LHP | 4 | Mets | 1 | 24 | 2016 |
| 23 | Lewis Brinson | OF | 3 | Rangers | 2 | 21 | 2017 |
| 24 | Sean Manaea | LHP | 5 | A’s | 1 | 23 | 2017 |
| 25 | Kevin Maitan | SS | 7 | (Venezuela) | 2 | 15 | 2020 |
| 26 | Nomar Mazara | OF | 4 | Rangers | 3 | 20 | 2017 |
| 27 | Kyle Tucker | OF | 5 | Astros | 1 | 19 | 2019 |
| 28 | Shintaro Fujinami | RHP | 8 | (Japan) | 3 | 21 | 2022 |
| 29 | Bradley Zimmer | OF | 6 | Indians | 1 | 23 | 2017 |
| 30 | Austin Meadows | OF | 7 | Pirates | 2 | 20 | 2018 |
| 31 | Jesse Winker | OF | 8 | Reds | 1 | 22 | 2016 |
| 32 | Franklin Barreto | SS | 8 | A’s | 2 | 19 | 2019 |
| 33 | Archie Bradley | RHP | 9 | Diamondbacks | 1 | 23 | 2016 |
| 34 | Dylan Bundy | RHP | 10 | Orioles | 1 | 23 | 2016 |
| 35 | A.J. Reed | 1B | 1 | Astros | 2 | 22 | 2016 |
| 36 | Victor Robles | OF | 9 | Nationals | 3 | 18 | 2019 |
| 37 | Orlando Arcia | SS | 9 | Brewers | 1 | 21 | 2017 |
| 38 | Nick Williams | OF | 10 | Phillies | 2 | 22 | 2016 |
| 39 | Alex Bregman | SS | 10 | Astros | 3 | 21 | 2018 |
| 40 | Yadier Alvarez | RHP | 11 | Dodgers | 4 | 19 | 2019 |
| 41 | Lazaro Armenteros | OF | 11 | (Free Agent) | 1 | 16 | 2022 |
| 42 | Jose Peraza | 2B | 2 | Reds | 2 | 21 | 2017 |
| 43 | Brett Phillips | OF | 12 | Brewers | 2 | 21 | 2017 |
| 44 | Kolby Allard | LHP | 6 | Braves | 3 | 18 | 2020 |
| 45 | Michael Fulmer | RHP | 12 | Tigers | 1 | 22 | 2017 |
| 46 | Jon Gray | RHP | 13 | Rockies | 3 | 24 | 2016 |
| 47 | Daz Cameron | OF | 13 | Astros | 4 | 19 | 2019 |
| 48 | Hunter Harvey | RHP | 14 | Orioles | 2 | 21 | 2018 |
| 49 | Vladimir Gutierrez | RHP | 15 | (Free Agent) | 2 | 20 | 2017 |
| 50 | Clint Frazier | OF | 14 | Indians | 2 | 21 | 2017 |
| 51 | Tyler Kolek | RHP | 16 | Marlins | 1 | 20 | 2018 |
| 52 | Andrew Benintendi | OF | 15 | Red Sox | 4 | 21 | 2018 |
| 53 | Jacob Nottingham | C | 1 | A’s | 3 | 20 | 2018 |
| 54 | Jorge Mateo | SS | – | Yankees | 1 | 20 | 2019 |
| 55 | Abraham Gutierrez | C | 2 | (Venezuela) | 4 | 15 | 2024 |
| 56 | Brady Aiken | LHP | 7 | Indians | 3 | 19 | 2019 |
| 57 | Matt Olson | 1B | 2 | A’s | 4 | 21 | 2017 |
| 58 | Marco Gonzalez | LHP | 8 | Cardinals | 2 | 23 | 2016 |
| 59 | Bobby Bradley | 1B | 3 | Indians | 4 | 19 | 2019 |
| 60 | Ozahino Albies | SS | – | Braves | 4 | 19 | 2018 |
| 61 | Josh Bell | 1B | 4 | Pirates | 3 | 23 | 2016 |
| 62 | Aaron Judge | OF | 16 | Yankees | 2 | 23 | 2016 |
| 63 | AJ Puk | LHP | 9 | (NCAA) | 1 | 20 | 2018 |
| 64 | Jeff Hoffman | RHP | 17 | Rockies | 4 | 23 | 2017 |
| 65 | Dillon Tate | RHP | 18 | Rangers | 4 | 21 | 2018 |
| 66 | Max Kepler | OF | 17 | Twins | 3 | 22 | 2016 |
| 67 | Mallex Smith | OF | 18 | Braves | 5 | 22 | 2016 |
| 68 | Trevor Story | SS | – | Rockies | 5 | 23 | 2016 |
| 69 | Alec Hansen | RHP | 19 | (NCAA) | 2 | 20 | 2018 |
| 70 | Jorge Ona | OF | 19 | (Free Agent) | 3 | 19 | 2020 |
| 71 | Tim Anderson | SS | – | White Sox | 1 | 22 | 2018 |
| 72 | Jameson Taillon | RHP | 20 | Pirates | 4 | 24 | 2017 |
| 73 | Garrett Whitley | OF | 20 | Rays | 2 | 18 | 2020 |
| 74 | Mark Vientos | SS | – | (High School) | 1 | 16 | 2020 |
| 75 | Yusniel Diaz | OF | 21 | Dodgers | 5 | 19 | 2019 |
| 76 | Brent Honeywell | RHP | 21 | Rays | 3 | 20 | 2018 |
| 77 | Domingo Acevedo | RHP | 22 | Yankees | 3 | 21 | 2017 |
| 78 | Riley Pint | RHP | 23 | (High School) | 2 | 17 | 2021 |
| 79 | Raul Adalberto Mondesi | SS | – | Royals | 1 | 20 | 2018 |
| 80 | Ryan McMahon | 3B | 3 | Rockies | 6 | 21 | 2018 |
| 81 | Jake Thompson | RHP | 24 | Phillies | 3 | 21 | 2018 |
| 82 | Ronald Guzman | 1B | 5 | Rangers | 5 | 21 | 2017 |
| 83 | Robert Stephenson | RHP | 25 | Reds | 3 | 22 | 2016 |
| 84 | Grant Holmes | RHP | 26 | Dodgers | 6 | 19 | 2020 |
| 85 | Lourdes Gourriel Jr. | SS | – | (Cuba) | 5 | 21 | 2025 |
| 86 | Willy Adames | SS | – | Rays | 4 | 20 | 2018 |
| 87 | Jacob Faria | RHP | 27 | Rays | 5 | 22 | 2016 |
| 88 | Norge Luis Ruiz | RHP | 28 | (Free Agent) | 4 | 22 | 2017 |
| 89 | Jason Groome | LHP | 10 | (High School) | 3 | 17 | 2020 |
| 90 | Aaron Blair | RHP | 29 | Braves | 6 | 23 | 2016 |
| 91 | J.J. Schwartz | C | 3 | (NCAA) | 3 | 19 | 2018 |
| 92 | Tomohiro Anraku | RHP | 30 | (Japan) | 6 | 19 | 2024 |
| 93 | Isan Diaz | 2B | 3 | Diamondbacks | 2 | 19 | 2019 |
| 94 | Carson Fulmer | RHP | 31 | White Sox | 2 | 22 | 2018 |
| 95 | Manuel Margot | OF | 22 | Padres | 1 | 21 | 2017 |
| 96 | Vladimir Guerrero Jr. | OF | 23 | Blue Jays | 1 | 16 | 2021 |
| 97 | Forrest Wall | 2B | 4 | Rockies | 7 | 20 | 2017 |
| 98 | Austin Riley | 3B | 4 | Braves | 7 | 18 | 2020 |
| 99 | Franklyn Kilome | RHP | 32 | Phillies | 4 | 20 | 2018 |
| 100 | Tetsuto Yamada | SS | – | (Japan) | 7 | 22 | 2019 |
| 101 | Jorge Alfaro | C | 4 | Phillies | 5 | 22 | 2018 |
| 102 | Braden Shipley | RHP | 33 | Diamondbacks | 3 | 23 | 2017 |
| 103 | Billy McKinney | OF | 24 | Cubs | 2 | 21 | 2018 |
| 104 | Stephen Gonsalves | LHP | 11 | Twins | 4 | 21 | 2017 |
| 105 | Jack Flaherty | RHP | 34 | Cardinals | 3 | 20 | 2019 |
| 106 | Alex Jackson | OF | 25 | Mariners | 1 | 20 | 2018 |
| 107 | Frankie Montas | RHP | 35 | Dodgers | 7 | 22 | 2017 |
| 108 | Nobuhiro Matsuda | 3B | 5 | (Free Agent) | 5 | 32 | 2016 |
| 109 | Triston McKenzie | RHP | – | Indians | 5 | 18 | 2020 |
| 110 | Ronald Washington | OF | 26 | (High School) | 4 | 16 | 2021 |
| 111 | Phil Bickford | RHP | – | Giants | 1 | 20 | 2019 |
| 112 | Anthony Alford | OF | 27 | Blue Jays | 2 | 21 | 2019 |
| 113 | Jermaine Palacios | 3B | 6 | Twins | 5 | 19 | 2019 |
| 114 | Tyler Jay | LHP | 12 | Twins | 6 | 21 | 2019 |
| 115 | Kumar Rocker | RHP | – | (High School) | 5 | 15 | 2021 |
| 116 | Raimel Tapia | OF | 28 | Rockies | 8 | 21 | 2018 |
| 117 | Lucas Sims | RHP | – | Braves | 8 | 21 | 2017 |
| 118 | Josh Hader | LHP | 13 | Brewers | 3 | 21 | 2017 |
| 119 | Nathan Kirby | LHP | 14 | Brewers | 4 | 22 | 2018 |
| 120 | Tanner Houck | RHP | – | (NCAA) | 4 | 19 | 2019 |
| 121 | Hunter Renfroe | OF | 29 | Padres | 2 | 23 | 2017 |
| 122 | Brandon Nimmo | OF | 30 | Mets | 2 | 22 | 2017 |
| 123 | Kohl Stewart | RHP | – | Twins | 7 | 21 | 2018 |
| 124 | D.J. Stewart | OF | – | Orioles | 3 | 22 | 2018 |
| 125 | Josh Staumont | RHP | – | Royals | 2 | 22 | 2017 |
| 126 | Bubba Starling | OF | – | Royals | 3 | 23 | 2017 |
| 127 | Trey Mancini | 1B | 6 | Orioles | 4 | 23 | 2016 |
| 128 | Daniel Robertson | SS | – | Rays | 6 | 21 | 2018 |
| 129 | Michael Matuella | RHP | – | Rangers | 6 | 21 | 2018 |
| 130 | Trent Clark | OF | – | Brewers | 5 | 19 | 2020 |
| 131 | Brian Johnson | LHP | 15 | Red Sox | 5 | 25 | 2016 |
| 132 | Lewis Thorpe | LHP | – | Twins | 8 | 20 | 2019 |
| 133 | Alex Lange | RHP | – | (NCAA) | 5 | 19 | 2019 |
| 134 | Mark Appel | RHP | – | Phillies | 6 | 24 | 2016 |
| 135 | Rob Kaminsky | LHP | – | Indians | 6 | 21 | 2018 |
| 136 | Yulieski Gourriel | 3B | 7 | (Cuba) | 8 | 31 | Never |
| 137 | Max Fried | LHP | – | Braves | 9 | 22 | 2017 |
| 138 | Walker Buehler | RHP | – | Dodgers | 8 | 21 | 2018 |
| 139 | Francis Martes | RHP | – | Astros | 5 | 20 | 2019 |
| 140 | Marcos Molina | RHP | – | Mets | 3 | 20 | 2019 |
| 141 | Lucius Fox | SS | – | Giants | 2 | 18 | 2020 |
| 142 | Yuki Yanagita | OF | – | (Japan) | 9 | 27 | Never |
| 143 | Mike Nikorak | RHP | – | Rockies | 9 | 19 | 2019 |
| 144 | Tyler Stephenson | C | 5 | Reds | 4 | 19 | 2021 |
| 145 | Eloy Jimenez | OF | – | Cubs | 3 | 19 | 2019 |
| 146 | Connor Greene | RHP | – | Blue Jays | 3 | 20 | 2019 |
| 147 | James Kaprielian | RHP | – | Yankees | 4 | 21 | 2019 |
| 148 | Derek Fisher | OF | – | Astros | 6 | 22 | 2017 |
| 149 | Kyle Crick | RHP | – | Giants | 3 | 23 | 2017 |
| 150 | Ha-Seong Kim | SS | – | (S Korea) | 10 | 19 | 2020 |
| 151 | Josh Naylor | 1B | 7 | Marlins | 2 | 18 | 2020 |
| 152 | Tyler O’Neill | OF | – | Mariners | 2 | 20 | 2019 |
| 153 | Albert Abreu | RHP | – | Astros | 7 | 20 | 2019 |
| 154 | Brandon Drury | 3B | 8 | Diamondbacks | 4 | 23 | 2016 |
| 155 | Zach Davies | RHP | – | Brewers | 6 | 22 | 2017 |
| 156 | Rookie Davis | RHP | – | Reds | 5 | 22 | 2017 |
| 157 | Ruddy Giron | SS | – | Padres | 3 | 19 | 2020 |
| 158 | Jordan Patterson | OF | – | Rockies | 10 | 23 | 2017 |
| 159 | Kyle Freeland | LHP | – | Rockies | – | 22 | 2017 |
| 160 | Cornelius Randolph | OF | – | Phillies | 7 | 18 | 2021 |
| 161 | Alfredo Despaigne | OF | – | (Cuba) | – | 29 | Never |
| 162 | Jorge Polanco | SS | – | Twins | 9 | 22 | 2017 |
| 163 | Alen Hanson | 2B | 5 | Pirates | 5 | 23 | 2017 |
| 164 | Renato Nunez | 3B | 9 | A’s | 5 | 21 | 2018 |
| 165 | Jario Beras | OF | – | Rangers | 7 | 21 | 2018 |
| 166 | Reymond Fuentes | OF | – | Royals | 4 | 24 | 2016 |
| 167 | Trayce Thompson | OF | – | Dodgers | 9 | 24 | 2016 |
| 168 | Chad Pinder | SS | – | A’s | 6 | 23 | 2016 |
| 169 | Cody Reed | LHP | – | Diamondbacks | 5 | 19 | 2019 |
| 170 | Justin Williams | OF | – | Rays | 7 | 20 | 2019 |
| 171 | Corey Ray | OF | – | (NCAA) | 6 | 20 | 2018 |
| 172 | Eddy Julio Martinez | OF | – | Cubs | 4 | 21 | 2017 |
| 173 | Touki Toussaint | RHP | – | Braves | 10 | 19 | 2020 |
| 174 | Nick Gordon | SS | – | Twins | 10 | 20 | 2020 |
| 175 | Jose Miguel Fernandez | 2B | 6 | (Free Agent) | 6 | 26 | 2016 |
| 176 | Brendan McKay | LHP | – | (NCAA) | 7 | 19 | 2019 |
| 177 | Carl Edwards Jr. | RHP | – | Cubs | 5 | 24 | 2017 |
| 178 | Jharel Cotton | RHP | – | Dodgers | 10 | 24 | 2017 |
| 179 | Ian Clarkin | LHP | – | Yankees | 5 | 20 | 2020 |
| 180 | Yasiel Sierra | RHP | – | Dodgers | – | 25 | 2017 |
| 181 | Yoan Lopez | RHP | – | Diamondbacks | 6 | 23 | 2017 |
| 182 | Junior Fernandez | RHP | – | Cardinals | 4 | 18 | 2021 |
| 183 | Starling Heredia | OF | – | Dodgers | – | 16 | 2022 |
| 184 | Alfredo Rodriguez | SS | – | Reds | 6 | 21 | 2016 |
| 185 | Andrew Moore | RHP | – | Mariners | 3 | 21 | 2018 |
| 186 | Randy Arozarena | 2B | 7 | (Free Agent) | 7 | 20 | 2019 |
| 187 | Kyle Zimmer | RHP | – | Royals | 5 | 24 | 2016 |
| 188 | Steven Moya | OF | – | Tigers | 2 | 24 | 2016 |
| 189 | John Lamb | LHP | – | Reds | 7 | 25 | 2016 |
| 190 | Magneuris Sierra | OF | – | Cardinals | 5 | 19 | 2020 |
| 191 | Wilson Contreras | C | 6 | Cubs | 6 | 23 | 2017 |
| 192 | Nick Pummer | OF | – | Cardinals | 6 | 19 | 2019 |
| 193 | Adrian Rondon | SS | – | Rays | 8 | 17 | 2021 |
| 194 | Buddy Reed | OF | – | (NCAA) | 8 | 20 | 2019 |
| 195 | Luke Weaver | RHP | – | Cardinals | 7 | 22 | 2018 |
| 196 | Antonio Senzatela | RHP | – | Rockies | – | 20 | 2018 |
| 197 | Teoscar Hernandez | OF | – | Astros | 8 | 23 | 2017 |
| 198 | Yadiel Hernandez | OF | – | (Free Agent) | 8 | 28 | 2016 |
| 199 | Takayuk Kishi | RHP | – | (Japan) | – | 31 | 2017 |
| 200 | Yuji Nishino | RP | 1 | (Japan) | – | 24 | 2017 |
| 201 | Aristides Aquino | OF | – | Reds | 8 | 21 | 2018 |
| 202 | Travis Harrison | OF | – | Twins | – | 23 | 2017 |
| 203 | Luis Yander La O | 3B | 10 | (Free Agent) | 9 | 23 | 2016 |
| 204 | Tom Murphy | C | 7 | Rockies | – | 24 | 2016 |
| 205 | Hagen Danner | RHP | – | (High School) | 6 | 16 | 2021 |
| 206 | Amed Rosario | SS | – | Mets | 4 | 20 | 2019 |
| 207 | Jorge Lopez | RHP | – | Brewers | 7 | 22 | 2017 |
| 208 | Sean Reid-Foley | RHP | – | Blue Jays | 4 | 20 | 2019 |
| 209 | Dominic Smith | 1B | 8 | Mets | 5 | 20 | 2019 |
| 210 | J.B. Bukauskas | RHP | – | (NCAA) | 9 | 19 | 2019 |
| 211 | Michael Feliz | RHP | – | Astros | 9 | 22 | 2017 |
| 212 | Yoshitomo Tsutsugo | 2B | 8 | (Japan) | – | 24 | 2020 |
| 213 | Luis Ortiz | RHP | – | Rangers | 8 | 20 | 2020 |
| 214 | Javier Guerra | SS | – | Padres | 4 | 20 | 2019 |
| 215 | Ashe Russell | RHP | – | Royals | 6 | 19 | 2020 |
| 216 | Edmundo Sosa | SS | – | Cardinals | 8 | 19 | 2020 |
| 217 | Richie Shaffer | 3B | – | Rays | 9 | 24 | 2016 |
| 218 | Jake Bauers | 1B | 9 | Rays | 10 | 20 | 2019 |
| 219 | Peter O’Brien | OF | – | Diamondbacks | 7 | 25 | 2016 |
| 220 | Reynaldo Lopez | RHP | – | Nationals | 4 | 22 | 2017 |
| 221 | Dylan Cease | RHP | – | Cubs | 7 | 20 | 2019 |
| 222 | Joe Musgrove | RHP | – | Astros | 10 | 23 | 2017 |
| 223 | Thomas Eshelman | RHP | – | Phillies | 8 | 21 | 2019 |
| 224 | Matt Chapman | 3B | – | A’s | 7 | 22 | 2017 |
| 225 | Miguel Almonte | RHP | – | Royals | 7 | 22 | 2017 |
| 226 | Wuilmer Becerra | OF | – | Mets | 6 | 21 | 2018 |
| 227 | Alex Young | LHP | – | Diamondbacks | 8 | 22 | 2017 |
| 228 | Richard Urena | SS | – | Blue Jays | 5 | 19 | 2020 |
| 229 | Duane Underwood | RHP | – | Cubs | 8 | 21 | 2019 |
| 230 | Tyler Beede | RHP | – | Giants | 4 | 22 | 2017 |
| 231 | Andrew Knapp | C | 8 | Phillies | 9 | 24 | 2016 |
| 232 | D.J. Peterson | 3B | – | Mariners | 4 | 24 | 2016 |
| 233 | Austin Bergner | RHP | – | (High School) | 7 | 17 | 2020 |
| 234 | Jhailyn Ortiz | OF | – | Phillies | 10 | 17 | 2021 |
| 235 | Tyrell Jenkins | RHP | – | Braves | – | 23 | 2016 |
| 236 | Clint Coulter | OF | – | Brewers | 8 | 22 | 2017 |
| 237 | Drew Finley | RHP | – | Yankees | 6 | 19 | 2021 |
| 238 | Tyler White | 3B | – | Astros | – | 25 | 2016 |
| 239 | Socrates Brito | OF | – | Diamondbacks | 9 | 23 | 2016 |
| 240 | Travis Janowski | OF | – | Padres | 5 | 24 | 2016 |
| 241 | Michael Gettys | OF | – | Padres | 6 | 20 | 2020 |
| 242 | Michael Kopech | RHP | – | Red Sox | 6 | 19 | 2020 |
| 243 | Manny Banuelos | LHP | – | Braves | – | 24 | 2016 |
| 244 | Spencer Adams | RHP | – | White Sox | 3 | 19 | 2020 |
| 245 | Gary Sanchez | C | 9 | Yankees | 7 | 23 | 2017 |
| 246 | Donnie Dewees | OF | – | Cubs | 9 | 22 | 2018 |
| 247 | Christhian Adames | SS | – | Rockies | – | 24 | 2016 |
| 248 | Nick Burdi | RHP | – | Twins | – | 23 | 2017 |
| 249 | German Marquez | RHP | – | Rays | – | 20 | 2018 |
| 250 | Alejandro Toral | 1B | 10 | (High School) | 8 | 16 | 2023 |
| 251 | Alex Meyer | RP | 2 | Twins | – | 26 | 2016 |
| 252 | Gilbert Lara | SS | – | Brewers | 9 | 18 | 2020 |
| 253 | Harold Ramirez | OF | – | Pirates | 6 | 21 | 2018 |
| 254 | Taylor Guerrieri | RHP | – | Rays | – | 23 | 2017 |
| 255 | Ke’Bryan Hayes | 3B | – | Pirates | 7 | 18 | 2020 |
| 256 | Trey Michalczewski | 3B | – | White Sox | 4 | 20 | 2020 |
| 257 | Chris Anderson | RHP | – | Dodgers | – | 23 | 2017 |
| 258 | Christopher Shaw | 1B | – | Giants | 5 | 22 | 2017 |
| 259 | Eric Jagielo | 3B | – | Reds | 9 | 23 | 2017 |
| 260 | Erick Fedde | RHP | – | Nationals | 5 | 22 | 2018 |
| 261 | Richie Martin | SS | – | A’s | 8 | 21 | 2019 |
| 262 | Edwin Diaz | RHP | – | Mariners | 5 | 21 | 2018 |
| 263 | Zach Lee | RHP | – | Dodgers | – | 24 | 2016 |
| 264 | Casey Meisner | RHP | – | A’s | 9 | 20 | 2019 |
| 265 | Cal Quantrill | RHP | – | (NCAA) | 10 | 20 | 2018 |
| 266 | Demi Orimoloye | OF | – | Brewers | 10 | 19 | 2020 |
| 267 | Alex Verdugo | OF | – | Dodgers | – | 19 | 2020 |
| 268 | Micah Johnson | 2B | 9 | Dodgers | – | 25 | 2017 |
| 269 | Amir Garrett | LHP | – | Reds | 10 | 23 | 2016 |
| 270 | Joe Gatto | RHP | – | Angels | 1 | 20 | 2019 |
| 271 | Dan Vogelbach | 1B | – | Cubs | 10 | 23 | 2017 |
| 272 | Roman Quinn | OF | – | Phillies | – | 22 | 2018 |
| 273 | Robert Tyler | RHP | – | (NCAA) | – | 20 | 2018 |
| 274 | Gavin Cecchini | SS | – | Mets | 7 | 22 | 2016 |
| 275 | Ian Happ | OF | – | Cubs | – | 21 | 2019 |
| 276 | Keury Mella | RHP | – | Reds | – | 22 | 2017 |
| 277 | Yusei Kikuchi | LHP | – | (Japan) | – | 24 | 2018 |
| 278 | A.J. Cole | RHP | – | Nationals | 6 | 24 | 2016 |
| 279 | Wendell Rijo | 2B | 10 | Red Sox | 7 | 20 | 2019 |
| 280 | Mike Papi | OF | – | Indians | 7 | 23 | 2017 |
| 281 | Kodi Medeiros | LHP | – | Brewers | – | 19 | 2019 |
| 282 | Zach Eflin | RHP | – | Phillies | – | 21 | 2018 |
| 283 | Rymer Liriano | OF | – | Padres | 7 | 24 | 2016 |
| 284 | Colin Moran | 3B | – | Astros | – | 23 | 2016 |
| 285 | Derek Hill | OF | – | Tigers | 3 | 20 | 2020 |
| 286 | Connor Jones | RHP | – | (NCAA) | – | 20 | 2019 |
| 287 | Austin Wilson | OF | – | Mariners | 6 | 23 | 2018 |
| 288 | Tyler Danish | RHP | – | White Sox | 5 | 21 | 2018 |
| 289 | Alex Dickerson | 1B | – | Padres | 8 | 25 | 2016 |
| 290 | Shota Takeda | RHP | – | (Japan) | – | 23 | 2019 |
| 291 | Braxton Davidson | OF | – | Braves | – | 19 | 2020 |
| 292 | Cole Tucker | SS | – | Pirates | 8 | 19 | 2020 |
| 293 | Jose Rondon | SS | – | Padres | 9 | 21 | 2018 |
| 294 | Justin O’Connor | C | 10 | Rays | – | 23 | 2016 |
| 295 | Gareth Morgan | OF | – | Mariners | 7 | 19 | 2021 |
| 296 | Mitch Keller | RHP | – | Pirates | 9 | 19 | 2021 |
| 297 | Gabriel Guerrero | OF | – | Diamondbacks | 10 | 22 | 2018 |
| 298 | Austin Kubitza | RHP | – | Tigers | 4 | 24 | 2016 |
| 299 | Micker Adolfo | OF | – | White Sox | 6 | 19 | 2020 |
| 300 | Luiz Gohara | LHP | – | Mariners | 8 | 19 | 2020 |
| 301 | Max Pentecost | C | – | Blue Jays | 6 | 22 | 2018 |
| 302 | Jamie Westbrook | 2B | – | Diamondbacks | – | 20 | 2020 |
| 303 | Albert Almora | OF | – | Cubs | – | 21 | 2019 |
| 304 | Cheslor Cuthbert | 3B | – | Royals | 8 | 23 | 2017 |
| 305 | Taylor Ward | C | – | Angels | 2 | 22 | 2018 |
| 306 | Nick Kingham | RHP | – | Pirates | 10 | 24 | 2017 |
| 307 | Wilmer Difo | SS | – | Nationals | 7 | 23 | 2017 |
| 308 | Cionel Perez | LHP | – | (Free Agent) | 10 | 20 | 2018 |
| 309 | Devin Williams | RHP | – | Brewers | – | 21 | 2019 |
| 310 | Mike Soroka | RHP | – | Braves | – | 18 | 2021 |
| 311 | Takahiro Norimoto | RHP | – | (Japan) | – | 25 | 2021 |
| 312 | Thomas Szapucki | LHP | – | Mets | 8 | 19 | 2019 |
| 313 | Michael Chavis | 3B | – | Red Sox | 8 | 20 | 2019 |
| 314 | Parker Bridwell | RHP | – | Orioles | 5 | 24 | 2016 |
| 315 | Nick Travieso | RHP | – | Reds | – | 21 | 2018 |
| 316 | Stryker Trahan | C | – | Diamondbacks | – | 21 | 2019 |
| 317 | Cody Bellinger | 1B | – | Dodgers | – | 20 | 2020 |
| 318 | Courtney Hawkins | OF | – | White Sox | 7 | 22 | 2018 |
| 319 | Nick Banks | OF | – | (NCAA) | – | 20 | 2019 |
| 320 | Chris Betts | C | – | Rays | – | 18 | 2021 |
| 321 | Luken Baker | RHP | – | (NCAA) | – | 18 | 2020 |
| 322 | Jonathan Harris | RHP | – | Blue Jays | 7 | 22 | 2019 |
| 323 | Jarlin Garcia | LHP | – | Marlins | 3 | 23 | 2016 |
| 324 | Luke Jackson | RHP | – | Rangers | 9 | 24 | 2016 |
| 325 | Raul Alcantra | RHP | – | A’s | 10 | 23 | 2017 |
| 326 | Matt Krook | LHP | – | (NCAA) | – | 20 | 2019 |
| 327 | Brian Goodwin | OF | – | Nationals | 8 | 25 | 2016 |
| 328 | Adam Brett Walker II | OF | – | Twins | – | 24 | 2016 |
| 329 | Yeudy Garcia | RHP | – | Pirates | – | 23 | 2017 |
| 330 | Justus Sheffield | LHP | – | Indians | 8 | 19 | 2020 |
| 331 | Kaleb Cowart | 3B | – | Angels | 3 | 23 | 2017 |
| 332 | Mike Clevinger | RHP | – | Indians | 9 | 25 | 2016 |
| 333 | Jario Labourt | LHP | – | Tigers | 5 | 21 | 2018 |
| 334 | Christian Arroyo | SS | – | Giants | 6 | 20 | 2019 |
| 335 | Akeel Morris | RP | 3 | Mets | 9 | 23 | 2016 |
| 336 | Yario Munoz | SS | – | A’s | – | 20 | 2020 |
| 337 | Blake Rutherford | OF | – | (High School) | 9 | 17 | 2021 |
| 338 | Tyrone Taylor | OF | – | Brewers | – | 21 | 2019 |
| 339 | Monte Harrison | OF | – | Brewers | – | 20 | 2020 |
| 340 | Christian Walker | 1B | – | Orioles | 6 | 24 | 2016 |
| 341 | Victor Roache | OF | – | Brewers | – | 24 | 2018 |
| 342 | Julio Pablo Martinez | OF | – | (Cuba) | – | 19 | 2020 |
| 343 | Chris Okey | C | – | (NCAA) | – | 20 | 2020 |
| 344 | Dakota Chalmers | RHP | – | A’s | – | 19 | 2019 |
| 345 | Alvaro Seijas | RHP | – | Cardinals | 9 | 17 | 2021 |
| 346 | Chase De Jong | RHP | – | Dodgers | – | 22 | 2018 |
| 347 | Roberto Baldoquin | 2B | – | Angels | 4 | 21 | 2018 |
| 348 | Jeren Kendall | OF | – | (NCAA) | – | 19 | 2020 |
| 349 | Ben Lively | RHP | – | Phillies | – | 23 | 2017 |
| 350 | Dixon Machado | SS | – | Tigers | 6 | 23 | 2016 |
| 351 | Chihiro Kaneko | RHP | – | (Japan) | – | 32 | Never |
| 352 | Chance Sisco | C | – | Orioles | 7 | 20 | 2020 |
| 353 | Jordan Sheffield | RHP | – | (NCAA) | – | 20 | 2020 |
| 354 | Rio Ruiz | 3B | – | Braves | – | 21 | 2019 |
| 355 | Livan Moinelo | RP | 4 | (Cuba) | – | 20 | 2020 |
| 356 | Cody Reed | LHP | – | Reds | – | 22 | 2018 |
| 357 | Chris Ellis | RHP | – | Braves | – | 23 | 2017 |
| 358 | Matt Davidson | 3B | – | White Sox | 8 | 24 | 2016 |
| 359 | Dermis Garcia | SS | – | Yankees | 8 | 18 | 2022 |
| 360 | Stone Garrett | OF | – | Marlins | 4 | 20 | 2020 |
| 361 | Garin Cecchini | 3B | – | Brewers | – | 24 | 2016 |
| 362 | Jose Adolis Garcia | OF | – | (Cuba) | – | 23 | 2017 |
| 363 | Rowdy Tellez | 1B | – | Blue Jays | 8 | 20 | 2020 |
| 364 | Ja-wook Koo | 1B | – | (S Korea) | – | 22 | 2018 |
| 365 | Jeimer Candelario | 3B | – | Cubs | – | 22 | 2018 |
| 366 | Cody Ponce | RHP | – | Brewers | – | 21 | 2019 |
| 367 | Deven Marrero | SS | – | Red Sox | 9 | 25 | 2017 |
| 368 | Skye Bolt | OF | – | A’s | – | 22 | 2018 |
| 369 | Jorge Bonifacio | OF | – | Royals | 9 | 22 | 2018 |
| 370 | Justin Steele | LHP | – | Cubs | – | 20 | 2020 |
| 371 | Reese McGuire | C | – | Pirates | – | 20 | 2020 |
| 372 | Mickey Moniak | OF | – | (High School) | 10 | 17 | 2021 |
| 373 | Sam Travis | 1B | – | Red Sox | 10 | 22 | 2018 |
| 374 | Kevin Ziomek | LHP | – | Tigers | 7 | 23 | 2017 |
| 375 | Paul DeJong | 3B | – | Cardinals | 10 | 22 | 2018 |
| 376 | Victor Alcantra | RHP | – | Angels | 5 | 22 | 2017 |
| 377 | Hunter Dozier | 3B | – | Royals | 10 | 24 | 2017 |
| 378 | Scott Schebler | OF | – | Reds | – | 25 | 2016 |
| 379 | Tyler Naquin | OF | – | Indians | 10 | 24 | 2016 |
| 380 | Pierce Johnson | RHP | – | Cubs | – | 24 | 2017 |
| 381 | Wilkerman Garcia | SS | – | Yankees | 9 | 17 | 2022 |
| 382 | Kyle Kubzita | 3B | – | Angels | 6 | 25 | 2017 |
| 383 | Patrick Leonard | 1B | – | Rays | – | 23 | 2017 |
| 384 | Beau Burrows | RHP | – | Tigers | 8 | 19 | 2021 |
| 385 | Ryan Boldt | OF | – | (NCAA) | – | 20 | 2020 |
| 386 | Mason Williams | OF | – | Yankees | 10 | 24 | 2016 |
| 387 | Luis Robert | OF | – | (Cuba) | – | 19 | 2020 |
| 388 | Dillon Overton | LHP | – | A’s | – | 24 | 2017 |
| 389 | Yosvani Alarcon | C | – | (Cuba) | – | 31 | Never |
| 390 | Kevin Newman | SS | – | Pirates | – | 22 | 2018 |
| 391 | Samuel Coonrod | RHP | – | Giants | 7 | 23 | 2018 |
| 392 | Lazaro Alonso | 1B | – | (Free Agent) | – | 21 | 2019 |
| 393 | Matt Reynolds | SS | – | Mets | 10 | 25 | 2016 |
| 394 | Dario Alvarez | RP | 5 | Mets | – | 27 | 2016 |
| 395 | Yasel Antoona | SS | – | (Dominican Rep.) | – | 15 | 2023 |
| 396 | Jomar Reyes | 3B | – | Orioles | 8 | 18 | 2022 |
| 397 | Michael Cederoth | RHP | – | Twins | – | 23 | 2017 |
| 398 | Jen-Ho Tseng | RHP | – | Cubs | – | 21 | 2019 |
| 399 | Adalberto Mejia | LHP | – | Giants | 8 | 22 | 2017 |
| 400 | Josh Osich | RP | – | Giants | 9 | 27 | 2016 |
| HM | Jahamai Jones | OF | – | Angels | 7 | 18 | 2022 |
| HM | Drew Ward | 3B | – | Nationals | 9 | 21 | 2018 |
| HM | Grayson Greiner | C | – | Tigers | 9 | 23 | 2018 |
| HM | Boog Powell | OF | – | Mariners | 9 | 23 | 2017 |
| HM | Clinton Hollon | RHP | – | Blue Jays | 9 | 21 | 2018 |
| HM | Mychal Givens | RHP | – | Orioles | 9 | 25 | 2016 |
| HM | Michael Ynoa | RHP | – | White Sox | 9 | 24 | 2016 |
| HM | Ti’Quan Forbes | 3B | – | Rangers | 10 | 19 | 2021 |
| HM | Mac Williamson | OF | – | Giants | 10 | 25 | 2016 |
| HM | Jabari Blash | OF | – | Padres | 10 | 26 | 2016 |
| HM | Mike Wright | RHP | – | Orioles | 10 | 26 | 2016 |
| HM | Guillermo Aviles | 1B | – | (Cuba) | – | 24 | Never |
| HM | Joe Wendle | 2B | – | A’s | – | 25 | 2016 |
| HM | Tony Kemp | 2B | – | Astros | – | 24 | 2017 |
| HM | Omar Estevez | 2B | – | Dodgers | – | 17 | 2022 |
| HM | Robert Refsnyder | 2B | – | Yankees | – | 24 | 2017 |
| HM | Fredrich Cepeda | 3B | – | (Cuba) | – | 35 | Never |
| HM | Mike Ohlman | C | – | Cardinals | – | 25 | 2017 |
| HM | Francisco Mejia | C | – | Indians | – | 20 | 2021 |
| HM | Adrian Morejon | LHP | – | (Free Agent) | – | 16 | 2023 |
| HM | Sean Nolin | LHP | – | A’s | – | 26 | 2016 |
| HM | Tim Cooney | LHP | – | Cardinals | – | 25 | 2016 |
| HM | Bryan Hudson | LHP | – | Cubs | – | 18 | 2022 |
| HM | Sho Nakata | OF | – | (Japan) | – | 26 | Never |
| HM | Yoshio Itoi | OF | – | (Japan) | – | 34 | Never |
| HM | Shogo Akiyama | OF | – | (Japan) | – | 27 | Never |
| HM | Victor Mesa Jr. | OF | – | (Cuba) | – | 20 | Never |
| HM | Seth Beer | OF | – | (High School) | – | 17 | 2022 |
| HM | Willie Abreu | OF | – | (NCAA) | – | 20 | 2019 |
| HM | Harrison Bader | OF | – | Cardinals | – | 21 | 2019 |
| HM | Charlie Tilson | OF | – | Cardinals | – | 23 | 2017 |
| HM | James Ramsey | OF | – | Indians | – | 26 | 2016 |
| HM | Leodys Taveras | OF | – | Rangers | – | 17 | 2022 |
| HM | Luis Alexander Basabe | OF | – | Red Sox | – | 19 | 2021 |
| HM | Yorman Rodriguez | OF | – | Reds | – | 23 | 2018 |
| HM | Elier Hernandez | OF | – | Royals | – | 21 | 2019 |
| HM | Slade Heathcott | OF | – | Yankees | – | 25 | 2016 |
| HM | Yuki Nishi | RHP | – | (Japan) | – | 20 | 2021 |
| HM | Dylan Covey | RHP | – | A’s | – | 24 | 2017 |
| HM | Asher Wojciechowski | RHP | – | Astros | – | 27 | 2016 |
| HM | Riley Farrell | RHP | – | Astros | – | 22 | 2018 |
| HM | Daniel Winkler | RHP | – | Braves | – | 25 | 2016 |
| HM | Wei Chieh Huang | RHP | – | Diamondbacks | – | 22 | 2018 |
| HM | Colin Rea | RHP | – | Padres | – | 25 | 2017 |
| HM | Luis Heredia | RHP | – | Pirates | – | 21 | 2019 |
| HM | Ryne Stanek | RHP | – | Rays | – | 24 | 2017 |
| HM | Hector Mendoza | RP | – | (Japan) | – | 21 | 2023 |
| HM | Bobby Wahl | RP | – | A’s | – | 23 | 2017 |
| HM | R.J. Alvarez | RP | – | A’s | – | 24 | 2016 |
| HM | Sam Tuivailala | RP | – | Cardinals | – | 23 | 2016 |
| HM | Rafael De Paula | RP | – | Padres | – | 24 | 2017 |
| HM | Jacob Lindgren | RP | – | Yankees | – | 22 | 2017 |
| HM | Hayato Sakamoto | SS | – | (Japan) | – | 27 | Never |
| HM | Derian Cruz | SS | – | Braves | – | 17 | 2022 |
| HM | Jake Gatewood | SS | – | Brewers | – | 20 | 2020 |
| HM | Franchy Cordero | SS | – | Padres | – | 21 | 2019 |
| HM | Wander Javier | SS | – | Twins | – | 17 | 2022 |
