| Week 1 | Cleveland Browns vs. Jacksonville Jaguars | Sunday, September 13th, 2026 at 1:00pm ET |
| Week 2 | Jacksonville Jaguars vs. Denver Broncos | Sunday, September 20th, 2026 at 4:05pm ET |
| Week 3 | New England Patriots vs. Jacksonville Jaguars | Sunday, September 27th, 2026 at 1:00pm ET |
| Week 4 | Jacksonville Jaguars vs. Cincinnati Bengals | Sunday, October 4th, 2026 at 1:00pm ET |
| Week 5 | Philadelphia Eagles vs. Jacksonville Jaguars | Sunday, October 11th, 2026 at 9:30am ET |
| Week 6 | Houston Texans vs. Jacksonville Jaguars | Sunday, October 18th, 2026 at 9:30am ET |
| Week 7 | Bye Week | |
| Week 8 | Indianapolis Colts vs. Jacksonville Jaguars | Sunday, November 1st, 2026 at 1:00pm ET |
| Week 9 | Jacksonville Jaguars vs. Baltimore Ravens | Thursday, November 5th, 2026 at 8:15pm ET |
| Week 10 | Jacksonville Jaguars vs. Tennessee Titans | Sunday, November 15th, 2026 at 1:00pm ET |
| Week 11 | Jacksonville Jaguars vs. New York Giants | Sunday, November 22nd, 2026 at 1:00pm ET |
| Week 12 | Tennessee Titans vs. Jacksonville Jaguars | Sunday, November 29th, 2026 at 4:05pm ET |
| Week 13 | Jacksonville Jaguars vs. Chicago Bears | Sunday, December 6th, 2026 at 1:00pm ET |
| Week 14 | Pittsburgh Steelers vs. Jacksonville Jaguars | Monday, December 14th, 2026 at 8:15pm ET |
| Week 15 | Jacksonville Jaguars vs. Houston Texans | Sunday, December 20th, 2026 at 1:00pm ET |
| Week 16 | Jacksonville Jaguars vs. Dallas Cowboys | Sunday, December 27th, 2026 at 8:20pm ET |
| Week 17 | Washington Commanders vs. Jacksonville Jaguars | Sunday, January 3rd, 2027 at 1:00pm ET |
| Week 18 | Jacksonville Jaguars vs. Indianapolis Colts | Sunday, January 10th, 2027 at 1:00pm ET |
