| Week 1 | New England Patriots vs. Seattle Seahawks | Wednesday, September 9th, 2026 at 8:20pm ET |
| Week 2 | Pittsburgh Steelers vs. New England Patriots | Sunday, September 20th, 2026 at 1:00pm ET |
| Week 3 | New England Patriots vs. Jacksonville Jaguars | Sunday, September 27th, 2026 at 1:00pm ET |
| Week 4 | New England Patriots vs. Buffalo Bills | Sunday, October 4th, 2026 at 1:00pm ET |
| Week 5 | Las Vegas Raiders vs. New England Patriots | Sunday, October 11th, 2026 at 1:00pm ET |
| Week 6 | New York Jets vs. New England Patriots | Sunday, October 18th, 2026 at 1:00pm ET |
| Week 7 | New England Patriots vs. Chicago Bears | Thursday, October 22nd, 2026 at 8:15pm ET |
| Week 8 | New England Patriots vs. Miami Dolphins | Sunday, November 1st, 2026 at 4:25pm ET |
| Week 9 | Green Bay Packers vs. New England Patriots | Sunday, November 8th, 2026 at 4:25pm ET |
| Week 10 | New England Patriots vs. Detroit Lions | Sunday, November 15th, 2026 at 9:30am ET |
| Week 11 | Bye Week | |
| Week 12 | New England Patriots vs. Los Angeles Chargers | Sunday, November 29th, 2026 at 8:20pm ET |
| Week 13 | Buffalo Bills vs. New England Patriots | Sunday, December 6th, 2026 at 4:25pm ET |
| Week 14 | Minnesota Vikings vs. New England Patriots | Thursday, December 10th, 2026 at 8:15pm ET |
| Week 15 | New England Patriots vs. Kansas City Chiefs | Monday, December 21st, 2026 at 8:15pm ET |
| Week 16 | New England Patriots vs. New York Jets | Sunday, December 27th, 2026 at 1:00pm ET |
| Week 17 | Denver Broncos vs. New England Patriots | Sunday, January 3rd, 2027 at 1:00pm ET |
| Week 18 | Miami Dolphins vs. New England Patriots | Sunday, January 10th, 2027 at 1:00pm ET |
