| Week 1 | Tennessee Titans vs. New Orleans Saints | Sunday, September 10th, 2023 at 1:00pm ET |
| Week 2 | Los Angeles Chargers vs. Tennessee Titans | Sunday, September 17th, 2023 at 1:00pm ET |
| Week 3 | Tennessee Titans vs. Cleveland Browns | Sunday, September 24th, 2023 at 1:00pm ET |
| Week 4 | Cincinnati Bengals vs. Tennessee Titans | Sunday, October 1st, 2023 at 1:00pm ET |
| Week 5 | Tennessee Titans vs. Indianapolis Colts | Sunday, October 8th, 2023 at 1:00pm ET |
| Week 6 | Baltimore Ravens vs. Tennessee Titans | Sunday, October 15th, 2023 at 9:30am ET |
| Week 7 | Bye Week | |
| Week 8 | Atlanta Falcons vs. Tennessee Titans | Sunday, October 29th, 2023 at 1:00pm ET |
| Week 9 | Tennessee Titans vs. Pittsburgh Steelers | Thursday, November 2nd, 2023 at 8:15pm ET |
| Week 10 | Tennessee Titans vs. Tampa Bay Buccaneers | Sunday, November 12th, 2023 at 1:00pm ET |
| Week 11 | Tennessee Titans vs. Jacksonville Jaguars | Sunday, November 19th, 2023 at 1:00pm ET |
| Week 12 | Carolina Panthers vs. Tennessee Titans | Sunday, November 26th, 2023 at 1:00pm ET |
| Week 13 | Indianapolis Colts vs. Tennessee Titans | Sunday, December 3rd, 2023 at 1:00pm ET |
| Week 14 | Tennessee Titans vs. Miami Dolphins | Monday, December 11th, 2023 at 8:15pm ET |
| Week 15 | Houston Texans vs. Tennessee Titans | Sunday, December 17th, 2023 at 1:00pm ET |
| Week 16 | Seattle Seahawks vs. Tennessee Titans | Sunday, December 24th, 2023 at 1:00pm ET |
| Week 17 | Tennessee Titans vs. Houston Texans | Sunday, December 31st, 2023 at 1:00pm ET |
| Week 18 | Jacksonville Jaguars vs. Tennessee Titans | Sunday, January 7th, 2024 at 1:00pm ET |
