Colts' LT Anthony Castonzo (knee) reportedly "suffered some damage to MCL" against the Titans in Week 12 but avoided further injury, suggesting a two to six week recovery, per source. (Jim Ayello on Twitter)
The loss of the veteran left tackle is a significant blow to the Colts' elite offensive line. The team hopes to have Pro-Bowl C Ryan Kelly eligible to return from a neck injury that kept him out of their 45-26 loss to the Titans in Week 12. Castonzo will likely be replaced by Le'Raven Clark down the stretch of the 2020 season, which could heavily devalue QB Philip Rivers and the Colts' passing attack in fantasy formats.