You want the 49ers defense in fantasy football drafts. Their two first matchups - Chicago, Seattle - should allow them up to dial up pressure on fringy QBs. They were PFF's 4th-highest graded pass-rush unit a season ago and added USC pass-rusher Drake Jackson in the second round of the draft.
San Francisco 49ers Fantasy Football Outlook (2022)
San Francisco 49ers (DST - SF)