| Houston Texans at Detroit Lions | Thursday, November 26th, 2020 at 12:30pm ET | Bye Week: none |
| Washington Football Team at Dallas Cowboys | Thursday, November 26th, 2020 at 4:30pm ET | |
| Cleveland Browns at Jacksonville Jaguars | Sunday, November 29th, 2020 at 1:00pm ET | |
| Tennessee Titans at Indianapolis Colts | Sunday, November 29th, 2020 at 1:00pm ET | |
| Carolina Panthers at Minnesota Vikings | Sunday, November 29th, 2020 at 1:00pm ET | |
| Las Vegas Raiders at Atlanta Falcons | Sunday, November 29th, 2020 at 1:00pm ET | |
| Los Angeles Chargers at Buffalo Bills | Sunday, November 29th, 2020 at 1:00pm ET | |
| Miami Dolphins at New York Jets | Sunday, November 29th, 2020 at 1:00pm ET | |
| Arizona Cardinals at New England Patriots | Sunday, November 29th, 2020 at 1:00pm ET | |
| New York Giants at Cincinnati Bengals | Sunday, November 29th, 2020 at 1:00pm ET | |
| New Orleans Saints at Denver Broncos | Sunday, November 29th, 2020 at 4:05pm ET | |
| San Francisco 49ers at Los Angeles Rams | Sunday, November 29th, 2020 at 4:05pm ET | |
| Kansas City Chiefs at Tampa Bay Buccaneers | Sunday, November 29th, 2020 at 4:25pm ET | |
| Chicago Bears at Green Bay Packers | Sunday, November 29th, 2020 at 8:20pm ET | |
| Seattle Seahawks at Philadelphia Eagles | Monday, November 30th, 2020 at 8:15pm ET | |
| Baltimore Ravens at Pittsburgh Steelers | Tuesday, December 1st, 2020 at 8:00pm ET |
See the Full Season Schedule
