| Houston Texans at Kansas City Chiefs | Thursday, September 10th, 2020 at 8:20pm ET | Bye Week: none |
| Indianapolis Colts at Jacksonville Jaguars | Sunday, September 13th, 2020 at 1:00pm ET | |
| Las Vegas Raiders at Carolina Panthers | Sunday, September 13th, 2020 at 1:00pm ET | |
| New York Jets at Buffalo Bills | Sunday, September 13th, 2020 at 1:00pm ET | |
| Seattle Seahawks at Atlanta Falcons | Sunday, September 13th, 2020 at 1:00pm ET | |
| Philadelphia Eagles at Washington | Sunday, September 13th, 2020 at 1:00pm ET | |
| Miami Dolphins at New England Patriots | Sunday, September 13th, 2020 at 1:00pm ET | |
| Cleveland Browns at Baltimore Ravens | Sunday, September 13th, 2020 at 1:00pm ET | |
| Green Bay Packers at Minnesota Vikings | Sunday, September 13th, 2020 at 1:00pm ET | |
| Chicago Bears at Detroit Lions | Sunday, September 13th, 2020 at 1:00pm ET | |
| Los Angeles Chargers at Cincinnati Bengals | Sunday, September 13th, 2020 at 4:05pm ET | |
| Tampa Bay Buccaneers at New Orleans Saints | Sunday, September 13th, 2020 at 4:25pm ET | |
| Arizona Cardinals at San Francisco 49ers | Sunday, September 13th, 2020 at 4:25pm ET | |
| Dallas Cowboys at Los Angeles Rams | Sunday, September 13th, 2020 at 8:20pm ET | |
| Pittsburgh Steelers at New York Giants | Monday, September 14th, 2020 at 7:15pm ET | |
| Tennessee Titans at Denver Broncos | Monday, September 14th, 2020 at 10:10pm ET |
See the Full Season Schedule
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| Christian McCaffrey (CAR) | RB | |
| Saquon Barkley (NYG) | RB | |
| Michael Thomas (NO) | WR | |
| Ezekiel Elliott (DAL) | RB | |
| Derrick Henry (TEN) | RB | |
| Dalvin Cook (MIN) | RB | |
| Alvin Kamara (NO) | RB | |
| Tyreek Hill (KC) | WR | |
| Joe Mixon (CIN) | RB | |
| Davante Adams (GB) | WR | |
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| Nick Chubb (CLE) | RB | |
| Julio Jones (ATL) | WR | |
| DeAndre Hopkins (ARI) | WR | |
| Josh Jacobs (LV) | RB | |
| Chris Godwin (TB) | WR | |
| Travis Kelce (KC) | TE | |
| Kenny Golladay (DET) | WR | |
| George Kittle (SF) | TE | |
| Aaron Jones (GB) | RB | |
| Mike Evans (TB) | WR |
| Kenyan Drake (ARI) | RB | |
| Miles Sanders (PHI) | RB | |
| Amari Cooper (DAL) | WR | |
| Lamar Jackson (BAL) | QB | |
| Mark Andrews (BAL) | TE | |
| Patrick Mahomes (KC) | QB | |
| Odell Beckham Jr. (CLE) | WR | |
| Austin Ekeler (LAC) | RB | |
| A.J. Brown (TEN) | WR | |
| JuJu Smith-Schuster (PIT) | WR |
| Ronald Acuna Jr. (ATL) | LF,CF | |
| Mike Trout (LAA) | CF | |
| Christian Yelich (MIL) | LF,RF | |
| Cody Bellinger (LAD) | 1B,CF | |
| Mookie Betts (LAD) | CF,RF | |
| Francisco Lindor (CLE) | SS | |
| Trevor Story (COL) | SS | |
| Gerrit Cole (NYY) | SP | |
| Trea Turner (WSH) | SS | |
| Jacob deGrom (NYM) | SP | |
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| Juan Soto (WSH) | LF | |
| Nolan Arenado (COL) | 3B | |
| Max Scherzer (WSH) | SP | |
| Freddie Freeman (ATL) | 1B | |
| Jose Ramirez (CLE) | 3B | |
| Alex Bregman (HOU) | 3B,SS | |
| J.D. Martinez (BOS) | LF,RF | |
| Walker Buehler (LAD) | SP | |
| Anthony Rendon (LAA) | 3B | |
| Fernando Tatis Jr. (SD) | SS |
| Rafael Devers (BOS) | 3B | |
| Bryce Harper (PHI) | RF | |
| Justin Verlander (HOU) | SP | |
| Starling Marte (ARI) | CF | |
| Javier Baez (CHC) | SS | |
| Stephen Strasburg (WSH) | SP | |
| Jack Flaherty (STL) | SP | |
| Xander Bogaerts (BOS) | SS | |
| Shane Bieber (CLE) | SP | |
| Jose Altuve (HOU) | 2B |
| Anthony Davis (LAL) | PF,C | |
| James Harden (HOU) | PG,SG | |
| Giannis Antetokounmpo (MIL) | SF,PF | |
| Karl-Anthony Towns (MIN) | C | |
| Kevin Durant (BKN) | SF,PF | |
| LeBron James (LAL) | SF,PF | |
| Stephen Curry (GSW) | PG,SG | |
| Nikola Jokic (DEN) | PF,C | |
| Damian Lillard (POR) | PG | |
| Russell Westbrook (HOU) | PG | |
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| Victor Oladipo (IND) | PG,SG | |
| Paul George (LAC) | SF,PF | |
| Joel Embiid (PHI) | PF,C | |
| Kawhi Leonard (LAC) | SG,SF | |
| Chris Paul (OKC) | PG | |
| Jimmy Butler (MIA) | SG,SF | |
| Kemba Walker (BOS) | PG | |
| Ben Simmons (PHI) | PG,SF | |
| Kyrie Irving (BKN) | PG,SG | |
| Jrue Holiday (NOR) | PG,SG |
| Rudy Gobert (UTH) | C | |
| Andre Drummond (CLE) | PF,C | |
| John Wall (WAS) | PG | |
| Kyle Lowry (TOR) | PG | |
| Donovan Mitchell (UTH) | PG,SG | |
| Khris Middleton (MIL) | SG,SF | |
| Bradley Beal (WAS) | SG | |
| Kevin Love (CLE) | PF,C | |
| Draymond Green (GSW) | PF,C | |
| LaMarcus Aldridge (SAS) | PF,C |
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