| Houston Texans at Kansas City Chiefs | Thursday, September 10th, 2020 at 8:20pm ET | Bye Week: none |
| Indianapolis Colts at Jacksonville Jaguars | Sunday, September 13th, 2020 at 1:00pm ET | |
| Las Vegas Raiders at Carolina Panthers | Sunday, September 13th, 2020 at 1:00pm ET | |
| New York Jets at Buffalo Bills | Sunday, September 13th, 2020 at 1:00pm ET | |
| Seattle Seahawks at Atlanta Falcons | Sunday, September 13th, 2020 at 1:00pm ET | |
| Philadelphia Eagles at Washington Football Team | Sunday, September 13th, 2020 at 1:00pm ET | |
| Miami Dolphins at New England Patriots | Sunday, September 13th, 2020 at 1:00pm ET | |
| Cleveland Browns at Baltimore Ravens | Sunday, September 13th, 2020 at 1:00pm ET | |
| Green Bay Packers at Minnesota Vikings | Sunday, September 13th, 2020 at 1:00pm ET | |
| Chicago Bears at Detroit Lions | Sunday, September 13th, 2020 at 1:00pm ET | |
| Los Angeles Chargers at Cincinnati Bengals | Sunday, September 13th, 2020 at 4:05pm ET | |
| Tampa Bay Buccaneers at New Orleans Saints | Sunday, September 13th, 2020 at 4:25pm ET | |
| Arizona Cardinals at San Francisco 49ers | Sunday, September 13th, 2020 at 4:25pm ET | |
| Dallas Cowboys at Los Angeles Rams | Sunday, September 13th, 2020 at 8:20pm ET | |
| Pittsburgh Steelers at New York Giants | Monday, September 14th, 2020 at 7:10pm ET | |
| Tennessee Titans at Denver Broncos | Monday, September 14th, 2020 at 10:20pm ET |
See the Full Season Schedule
