| Tennessee Titans at Green Bay Packers | Thursday, November 17th, 2022 at 8:15pm ET |
Bye Week: JAC, MIA, SEA, TB |
| Los Angeles Rams at New Orleans Saints | Sunday, November 20th, 2022 at 1:00pm ET | |
| Cleveland Browns at Buffalo Bills | Sunday, November 20th, 2022 at 1:00pm ET | |
| Chicago Bears at Atlanta Falcons | Sunday, November 20th, 2022 at 1:00pm ET | |
| New York Jets at New England Patriots | Sunday, November 20th, 2022 at 1:00pm ET | |
| Carolina Panthers at Baltimore Ravens | Sunday, November 20th, 2022 at 1:00pm ET | |
| Washington Commanders at Houston Texans | Sunday, November 20th, 2022 at 1:00pm ET | |
| Philadelphia Eagles at Indianapolis Colts | Sunday, November 20th, 2022 at 1:00pm ET | |
| Detroit Lions at New York Giants | Sunday, November 20th, 2022 at 1:00pm ET | |
| Las Vegas Raiders at Denver Broncos | Sunday, November 20th, 2022 at 4:05pm ET | |
| Cincinnati Bengals at Pittsburgh Steelers | Sunday, November 20th, 2022 at 4:25pm ET | |
| Dallas Cowboys at Minnesota Vikings | Sunday, November 20th, 2022 at 4:25pm ET | |
| Kansas City Chiefs at Los Angeles Chargers | Sunday, November 20th, 2022 at 8:20pm ET | |
| San Francisco 49ers at Arizona Cardinals | Monday, November 21st, 2022 at 8:15pm ET |
See the Full Season Schedule
