| Green Bay Packers at Detroit Lions | Thursday, November 27th, 2025 at 1:00pm ET |
Bye Week: none |
| Kansas City Chiefs at Dallas Cowboys | Thursday, November 27th, 2025 at 4:30pm ET | |
| Cincinnati Bengals at Baltimore Ravens | Thursday, November 27th, 2025 at 8:20pm ET | |
| Chicago Bears at Philadelphia Eagles | Friday, November 28th, 2025 at 3:00pm ET | |
| Atlanta Falcons at New York Jets | Sunday, November 30th, 2025 at 1:00pm ET | |
| Arizona Cardinals at Tampa Bay Buccaneers | Sunday, November 30th, 2025 at 1:00pm ET | |
| San Francisco 49ers at Cleveland Browns | Sunday, November 30th, 2025 at 1:00pm ET | |
| Houston Texans at Indianapolis Colts | Sunday, November 30th, 2025 at 1:00pm ET | |
| New Orleans Saints at Miami Dolphins | Sunday, November 30th, 2025 at 1:00pm ET | |
| Jacksonville Jaguars at Tennessee Titans | Sunday, November 30th, 2025 at 1:00pm ET | |
| Los Angeles Rams at Carolina Panthers | Sunday, November 30th, 2025 at 1:00pm ET | |
| Minnesota Vikings at Seattle Seahawks | Sunday, November 30th, 2025 at 4:05pm ET | |
| Las Vegas Raiders at Los Angeles Chargers | Sunday, November 30th, 2025 at 4:25pm ET | |
| Buffalo Bills at Pittsburgh Steelers | Sunday, November 30th, 2025 at 4:25pm ET | |
| Denver Broncos at Washington Commanders | Sunday, November 30th, 2025 at 8:20pm ET | |
| New York Giants at New England Patriots | Monday, December 1st, 2025 at 8:15pm ET |
See the Full Season Schedule
