| Dallas Cowboys at Detroit Lions | Thursday, December 4th, 2025 at 8:15pm ET |
Bye Week: CAR, NE, NYG, SF |
| Seattle Seahawks at Atlanta Falcons | Sunday, December 7th, 2025 at 1:00pm ET | |
| New Orleans Saints at Tampa Bay Buccaneers | Sunday, December 7th, 2025 at 1:00pm ET | |
| Tennessee Titans at Cleveland Browns | Sunday, December 7th, 2025 at 1:00pm ET | |
| Indianapolis Colts at Jacksonville Jaguars | Sunday, December 7th, 2025 at 1:00pm ET | |
| Miami Dolphins at New York Jets | Sunday, December 7th, 2025 at 1:00pm ET | |
| Pittsburgh Steelers at Baltimore Ravens | Sunday, December 7th, 2025 at 1:00pm ET | |
| Washington Commanders at Minnesota Vikings | Sunday, December 7th, 2025 at 1:00pm ET | |
| Chicago Bears at Green Bay Packers | Sunday, December 7th, 2025 at 1:00pm ET | |
| Denver Broncos at Las Vegas Raiders | Sunday, December 7th, 2025 at 4:05pm ET | |
| Cincinnati Bengals at Buffalo Bills | Sunday, December 7th, 2025 at 4:25pm ET | |
| Los Angeles Rams at Arizona Cardinals | Sunday, December 7th, 2025 at 4:25pm ET | |
| Houston Texans at Kansas City Chiefs | Sunday, December 7th, 2025 at 8:20pm ET | |
| Philadelphia Eagles at Los Angeles Chargers | Monday, December 8th, 2025 at 8:15pm ET |
See the Full Season Schedule
