| Los Angeles Rams at Seattle Seahawks | Thursday, December 18th, 2025 at 8:15pm ET |
Bye Week: none |
| Philadelphia Eagles at Washington Commanders | Saturday, December 20th, 2025 at 5:00pm ET | |
| Green Bay Packers at Chicago Bears | Saturday, December 20th, 2025 at 8:20pm ET | |
| Los Angeles Chargers at Dallas Cowboys | Sunday, December 21st, 2025 at 1:00pm ET | |
| Kansas City Chiefs at Tennessee Titans | Sunday, December 21st, 2025 at 1:00pm ET | |
| Tampa Bay Buccaneers at Carolina Panthers | Sunday, December 21st, 2025 at 1:00pm ET | |
| Buffalo Bills at Cleveland Browns | Sunday, December 21st, 2025 at 1:00pm ET | |
| New England Patriots at Baltimore Ravens | Sunday, December 21st, 2025 at 1:00pm ET | |
| New York Jets at New Orleans Saints | Sunday, December 21st, 2025 at 1:00pm ET | |
| Minnesota Vikings at New York Giants | Sunday, December 21st, 2025 at 1:00pm ET | |
| Atlanta Falcons at Arizona Cardinals | Sunday, December 21st, 2025 at 4:05pm ET | |
| Jacksonville Jaguars at Denver Broncos | Sunday, December 21st, 2025 at 4:05pm ET | |
| Las Vegas Raiders at Houston Texans | Sunday, December 21st, 2025 at 4:25pm ET | |
| Pittsburgh Steelers at Detroit Lions | Sunday, December 21st, 2025 at 4:25pm ET | |
| Cincinnati Bengals at Miami Dolphins | Sunday, December 21st, 2025 at 8:20pm ET | |
| San Francisco 49ers at Indianapolis Colts | Monday, December 22nd, 2025 at 8:15pm ET |
See the Full Season Schedule
