| Cincinnati Bengals at Cleveland Browns | Thursday, September 17th, 2020 at 8:20pm ET | Bye Week: none |
| Jacksonville Jaguars at Tennessee Titans | Sunday, September 20th, 2020 at 1:00pm ET | |
| Minnesota Vikings at Indianapolis Colts | Sunday, September 20th, 2020 at 1:00pm ET | |
| Carolina Panthers at Tampa Bay Buccaneers | Sunday, September 20th, 2020 at 1:00pm ET | |
| Buffalo Bills at Miami Dolphins | Sunday, September 20th, 2020 at 1:00pm ET | |
| San Francisco 49ers at New York Jets | Sunday, September 20th, 2020 at 1:00pm ET | |
| Atlanta Falcons at Dallas Cowboys | Sunday, September 20th, 2020 at 1:00pm ET | |
| Los Angeles Rams at Philadelphia Eagles | Sunday, September 20th, 2020 at 1:00pm ET | |
| Detroit Lions at Green Bay Packers | Sunday, September 20th, 2020 at 1:00pm ET | |
| New York Giants at Chicago Bears | Sunday, September 20th, 2020 at 1:00pm ET | |
| Denver Broncos at Pittsburgh Steelers | Sunday, September 20th, 2020 at 1:00pm ET | |
| Washington Football Team at Arizona Cardinals | Sunday, September 20th, 2020 at 4:05pm ET | |
| Kansas City Chiefs at Los Angeles Chargers | Sunday, September 20th, 2020 at 4:25pm ET | |
| Baltimore Ravens at Houston Texans | Sunday, September 20th, 2020 at 4:25pm ET | |
| New England Patriots at Seattle Seahawks | Sunday, September 20th, 2020 at 8:20pm ET | |
| New Orleans Saints at Las Vegas Raiders | Monday, September 21st, 2020 at 8:15pm ET |
See the Full Season Schedule
