| Miami Dolphins at Jacksonville Jaguars | Thursday, September 24th, 2020 at 8:20pm ET | Bye Week: none |
| Houston Texans at Pittsburgh Steelers | Sunday, September 27th, 2020 at 1:00pm ET | |
| Las Vegas Raiders at New England Patriots | Sunday, September 27th, 2020 at 1:00pm ET | |
| Los Angeles Rams at Buffalo Bills | Sunday, September 27th, 2020 at 1:00pm ET | |
| Chicago Bears at Atlanta Falcons | Sunday, September 27th, 2020 at 1:00pm ET | |
| Washington Football Team at Cleveland Browns | Sunday, September 27th, 2020 at 1:00pm ET | |
| Cincinnati Bengals at Philadelphia Eagles | Sunday, September 27th, 2020 at 1:00pm ET | |
| Tennessee Titans at Minnesota Vikings | Sunday, September 27th, 2020 at 1:00pm ET | |
| San Francisco 49ers at New York Giants | Sunday, September 27th, 2020 at 1:00pm ET | |
| New York Jets at Indianapolis Colts | Sunday, September 27th, 2020 at 4:05pm ET | |
| Carolina Panthers at Los Angeles Chargers | Sunday, September 27th, 2020 at 4:05pm ET | |
| Dallas Cowboys at Seattle Seahawks | Sunday, September 27th, 2020 at 4:25pm ET | |
| Detroit Lions at Arizona Cardinals | Sunday, September 27th, 2020 at 4:25pm ET | |
| Tampa Bay Buccaneers at Denver Broncos | Sunday, September 27th, 2020 at 4:25pm ET | |
| Green Bay Packers at New Orleans Saints | Sunday, September 27th, 2020 at 8:20pm ET | |
| Kansas City Chiefs at Baltimore Ravens | Monday, September 28th, 2020 at 8:15pm ET |
See the Full Season Schedule
