| Los Angeles Rams at Seattle Seahawks | Thursday, October 3rd, 2019 at 8:20pm ET | Bye Week: DET, MIA |
| Chicago Bears at Oakland Raiders | Sunday, October 6th, 2019 at 1:00pm ET | |
| Jacksonville Jaguars at Carolina Panthers | Sunday, October 6th, 2019 at 1:00pm ET | |
| Buffalo Bills at Tennessee Titans | Sunday, October 6th, 2019 at 1:00pm ET | |
| Baltimore Ravens at Pittsburgh Steelers | Sunday, October 6th, 2019 at 1:00pm ET | |
| Minnesota Vikings at New York Giants | Sunday, October 6th, 2019 at 1:00pm ET | |
| Atlanta Falcons at Houston Texans | Sunday, October 6th, 2019 at 1:00pm ET | |
| New York Jets at Philadelphia Eagles | Sunday, October 6th, 2019 at 1:00pm ET | |
| New England Patriots at Washington | Sunday, October 6th, 2019 at 1:00pm ET | |
| Arizona Cardinals at Cincinnati Bengals | Sunday, October 6th, 2019 at 1:00pm ET | |
| Tampa Bay Buccaneers at New Orleans Saints | Sunday, October 6th, 2019 at 1:00pm ET | |
| Denver Broncos at Los Angeles Chargers | Sunday, October 6th, 2019 at 4:05pm ET | |
| Green Bay Packers at Dallas Cowboys | Sunday, October 6th, 2019 at 4:25pm ET | |
| Indianapolis Colts at Kansas City Chiefs | Sunday, October 6th, 2019 at 8:20pm ET | |
| Cleveland Browns at San Francisco 49ers | Monday, October 7th, 2019 at 8:15pm ET |
See the Full Season Schedule
| Saquon Barkley (NYG) | RB | |
| Ezekiel Elliott (DAL) | RB | |
| Christian McCaffrey (CAR) | RB | |
| Alvin Kamara (NO) | RB | |
| David Johnson (ARI) | RB | |
| DeAndre Hopkins (HOU) | WR | |
| Davante Adams (GB) | WR | |
| Travis Kelce (KC) | TE | |
| Joe Mixon (CIN) | RB | |
| Julio Jones (ATL) | WR | |
| View All Rankings |
| Melvin Gordon (LAC) | RB | |
| James Conner (PIT) | RB | |
| Le'Veon Bell (NYJ) | RB | |
| Odell Beckham Jr. (CLE) | WR | |
| Michael Thomas (NO) | WR | |
| JuJu Smith-Schuster (PIT) | WR | |
| Nick Chubb (CLE) | RB | |
| Todd Gurley (LAR) | RB | |
| Dalvin Cook (MIN) | RB | |
| Tyreek Hill (KC) | WR |
| Mike Evans (TB) | WR | |
| Antonio Brown (OAK) | WR | |
| George Kittle (SF) | TE | |
| T.Y. Hilton (IND) | WR | |
| Damien Williams (KC) | RB | |
| Keenan Allen (LAC) | WR | |
| Marlon Mack (IND) | RB | |
| A.J. Green (CIN) | WR | |
| Amari Cooper (DAL) | WR | |
| Derrick Henry (TEN) | RB |
| Mike Trout (LAA) | CF,DH | |
| Christian Yelich (MIL) | LF,CF | |
| Cody Bellinger (LAD) | 1B,CF | |
| Ronald Acuna Jr. (ATL) | LF,CF | |
| Nolan Arenado (COL) | 3B | |
| Mookie Betts (BOS) | CF,RF | |
| Max Scherzer (WSH) | SP | |
| Trevor Story (COL) | SS | |
| Francisco Lindor (CLE) | SS | |
| Javier Baez (CHC) | 2B,3B | |
| View All Rankings |
| J.D. Martinez (BOS) | LF,RF | |
| Alex Bregman (HOU) | 3B,SS | |
| Justin Verlander (HOU) | SP | |
| Gerrit Cole (HOU) | SP | |
| Freddie Freeman (ATL) | 1B | |
| Trea Turner (WSH) | SS | |
| Jacob deGrom (NYM) | SP | |
| Chris Sale (BOS) | SP | |
| Charlie Blackmon (COL) | CF | |
| Anthony Rendon (WSH) | 3B |
| Manny Machado (SD) | 3B,SS | |
| Aaron Judge (NYY) | RF,DH | |
| Whit Merrifield (KC) | 1B,2B | |
| Xander Bogaerts (BOS) | SS | |
| Josh Bell (PIT) | 1B | |
| Juan Soto (WSH) | LF | |
| Pete Alonso (NYM) | 1B,DH | |
| Kris Bryant (CHC) | 3B,RF | |
| Bryce Harper (PHI) | CF,RF | |
| Starling Marte (PIT) | CF |
| Anthony Davis (LAL) | PF,C | |
| James Harden (HOU) | PG,SG | |
| Giannis Antetokounmpo (MIL) | SF,PF | |
| Karl-Anthony Towns (MIN) | C | |
| Kevin Durant (BKN) | SF,PF | |
| LeBron James (LAL) | SF,PF | |
| Stephen Curry (GSW) | PG,SG | |
| Nikola Jokic (DEN) | PF,C | |
| Damian Lillard (POR) | PG | |
| Russell Westbrook (HOU) | PG | |
| View All Rankings |
| Victor Oladipo (IND) | PG,SG | |
| Paul George (LAC) | SG,SF | |
| Joel Embiid (PHI) | PF,C | |
| Kawhi Leonard (LAC) | SG,SF | |
| Chris Paul (OKC) | PG | |
| Jimmy Butler (MIA) | SG,SF | |
| Kemba Walker (BOS) | PG | |
| Ben Simmons (PHI) | PG,SF | |
| Kyrie Irving (BKN) | PG,SG | |
| Jrue Holiday (NOR) | PG,SG |
| Rudy Gobert (UTH) | C | |
| Andre Drummond (DET) | PF,C | |
| John Wall (WAS) | PG | |
| Kyle Lowry (TOR) | PG | |
| Donovan Mitchell (UTH) | PG,SG | |
| Khris Middleton (MIL) | SG,SF | |
| Bradley Beal (WAS) | SG | |
| Kevin Love (CLE) | PF,C | |
| Draymond Green (GSW) | PF,C | |
| LaMarcus Aldridge (SAS) | PF,C |
