| New England Patriots at Tampa Bay Buccaneers | Thursday, October 5th, 2017 at 8:25pm ET | Bye Week: ATL, DEN, NO, WAS |
| Carolina Panthers at Detroit Lions | Sunday, October 8th, 2017 at 1:00pm ET | |
| Tennessee Titans at Miami Dolphins | Sunday, October 8th, 2017 at 1:00pm ET | |
| San Francisco 49ers at Indianapolis Colts | Sunday, October 8th, 2017 at 1:00pm ET | |
| Los Angeles Chargers at New York Giants | Sunday, October 8th, 2017 at 1:00pm ET | |
| Buffalo Bills at Cincinnati Bengals | Sunday, October 8th, 2017 at 1:00pm ET | |
| Arizona Cardinals at Philadelphia Eagles | Sunday, October 8th, 2017 at 1:00pm ET | |
| Jacksonville Jaguars at Pittsburgh Steelers | Sunday, October 8th, 2017 at 1:00pm ET | |
| New York Jets at Cleveland Browns | Sunday, October 8th, 2017 at 1:00pm ET | |
| Seattle Seahawks at Los Angeles Rams | Sunday, October 8th, 2017 at 4:05pm ET | |
| Baltimore Ravens at Oakland Raiders | Sunday, October 8th, 2017 at 4:05pm ET | |
| Green Bay Packers at Dallas Cowboys | Sunday, October 8th, 2017 at 4:25pm ET | |
| Kansas City Chiefs at Houston Texans | Sunday, October 8th, 2017 at 8:30pm ET | |
| Minnesota Vikings at Chicago Bears | Monday, October 9th, 2017 at 8:30pm ET |
See the Full Season Schedule
Fantasy Games
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 | Serious Fantasy Football |
| Antonio Brown (PIT) | WR | |
| Julio Jones (ATL) | WR | |
| Le'Veon Bell (PIT) | RB | |
| Kareem Hunt (KC) | RB | |
| A.J. Green (CIN) | WR | |
| Leonard Fournette (JAC) | RB | |
| Michael Thomas (NO) | WR | |
| Mike Evans (TB) | WR | |
| Todd Gurley (LAR) | RB | |
| Brandin Cooks (NE) | WR | |
| View all Flex Rankings |
| Devonta Freeman (ATL) | RB | |
| Larry Fitzgerald (ARI) | WR | |
| Chris Hogan (NE) | WR | |
| Melvin Gordon (LAC) | RB | |
| Jordy Nelson (GB) | WR | |
| Jordan Howard (CHI) | RB | |
| Michael Crabtree (OAK) | WR | |
| Rob Gronkowski (NE) | TE | |
| Mark Ingram (NO) | RB | |
| Doug Baldwin (SEA) | WR |
| Jay Ajayi (MIA) | RB | |
| Adam Thielen (MIN) | WR | |
| Carlos Hyde (SF) | RB | |
| T.Y. Hilton (IND) | WR | |
| C.J. Anderson (DEN) | RB | |
| DeMarco Murray (TEN) | RB | |
| Jerick McKinnon (MIN) | RB | |
| Doug Martin (TB) | RB | |
| Keenan Allen (LAC) | WR | |
| Adrian Peterson (ARI) | RB |
| Jose Altuve (HOU) | 2B | |
| Paul Goldschmidt (ARI) | 1B | |
| Nolan Arenado (COL) | 3B | |
| Mike Trout (LAA) | CF,DH | |
| Mookie Betts (BOS) | RF | |
| Charlie Blackmon (COL) | CF | |
| Max Scherzer (WSH) | SP | |
| Joey Votto (CIN) | 1B | |
| Kris Bryant (CHC) | 1B,3B | |
| Chris Sale (BOS) | SP | |
| View All Rankings |
| Manny Machado (BAL) | 3B,SS | |
| Anthony Rizzo (CHC) | 1B,2B | |
| Corey Seager (LAD) | SS | |
| Giancarlo Stanton (MIA) | RF | |
| Clayton Kershaw (LAD) | SP | |
| Corey Kluber (CLE) | SP | |
| Daniel Murphy (WSH) | 1B,2B | |
| Nelson Cruz (SEA) | RF,DH | |
| George Springer (HOU) | CF,RF | |
| Freddie Freeman (ATL) | 1B,3B |
| Francisco Lindor (CLE) | SS | |
| Edwin Encarnacion (CLE) | 1B,DH | |
| Josh Donaldson (TOR) | 3B,DH | |
| Yu Darvish (LAD) | SP | |
| Robinson Cano (SEA) | 2B | |
| Bryce Harper (WSH) | RF | |
| Miguel Cabrera (DET) | 1B,DH | |
| J.D. Martinez (ARI) | RF | |
| Madison Bumgarner (SF) | SP | |
| Jose Abreu (CWS) | 1B,DH |
| Kevin Durant (GSW) | SF,PF | |
| Giannis Antetokounmpo (MIL) | SF,PF | |
| James Harden (HOU) | PG,SG | |
| Stephen Curry (GSW) | PG,SG | |
| Russell Westbrook (OKC) | PG | |
| Karl-Anthony Towns (MIN) | C | |
| Anthony Davis (NOR) | PF,C | |
| Kawhi Leonard (SAS) | SG,SF | |
| LeBron James (CLE) | SF,PF | |
| Nikola Jokic (DEN) | PF,C | |
| View All Rankings |
| John Wall (WAS) | PG | |
| DeMarcus Cousins (NOR) | PF,C | |
| Chris Paul (HOU) | PG | |
| Damian Lillard (POR) | PG | |
| Rudy Gobert (UTH) | C | |
| Jimmy Butler (MIN) | SG,SF | |
| Kyrie Irving (BOS) | PG,SG | |
| Myles Turner (IND) | PF,C | |
| Hassan Whiteside (MIA) | C,PF | |
| Paul George (OKC) | SF,PF |
| Kyle Lowry (TOR) | PG | |
| Draymond Green (GSW) | SF,PF | |
| Kristaps Porzingis (NYK) | PF,C | |
| Kemba Walker (CHA) | PG | |
| C.J. McCollum (POR) | PG,SG | |
| Mike Conley (MEM) | PG | |
| Bradley Beal (WAS) | SG | |
| Klay Thompson (GSW) | SG,SF | |
| Gordon Hayward (BOS) | SG,SF | |
| Marc Gasol (MEM) | C |
