| Tampa Bay Buccaneers at Chicago Bears | Thursday, October 8th, 2020 at 8:20pm ET | Bye Week: DEN, DET, GB, NE |
| Las Vegas Raiders at Kansas City Chiefs | Sunday, October 11th, 2020 at 1:00pm ET | |
| Jacksonville Jaguars at Houston Texans | Sunday, October 11th, 2020 at 1:00pm ET | |
| Carolina Panthers at Atlanta Falcons | Sunday, October 11th, 2020 at 1:00pm ET | |
| Arizona Cardinals at New York Jets | Sunday, October 11th, 2020 at 1:00pm ET | |
| Los Angeles Rams at Washington Football Team | Sunday, October 11th, 2020 at 1:00pm ET | |
| Philadelphia Eagles at Pittsburgh Steelers | Sunday, October 11th, 2020 at 1:00pm ET | |
| Cincinnati Bengals at Baltimore Ravens | Sunday, October 11th, 2020 at 1:00pm ET | |
| Miami Dolphins at San Francisco 49ers | Sunday, October 11th, 2020 at 4:05pm ET | |
| Indianapolis Colts at Cleveland Browns | Sunday, October 11th, 2020 at 4:25pm ET | |
| New York Giants at Dallas Cowboys | Sunday, October 11th, 2020 at 4:25pm ET | |
| Minnesota Vikings at Seattle Seahawks | Sunday, October 11th, 2020 at 8:20pm ET | |
| Los Angeles Chargers at New Orleans Saints | Monday, October 12th, 2020 at 8:15pm ET | |
| Buffalo Bills at Tennessee Titans | Tuesday, October 13th, 2020 at 7:00pm ET |
See the Full Season Schedule
