| Philadelphia Eagles at New York Giants | Thursday, October 9th, 2025 at 8:15pm ET |
Bye Week: HOU, MIN |
| Denver Broncos at New York Jets | Sunday, October 12th, 2025 at 9:30am ET | |
| Dallas Cowboys at Carolina Panthers | Sunday, October 12th, 2025 at 1:00pm ET | |
| Los Angeles Chargers at Miami Dolphins | Sunday, October 12th, 2025 at 1:00pm ET | |
| Cleveland Browns at Pittsburgh Steelers | Sunday, October 12th, 2025 at 1:00pm ET | |
| Arizona Cardinals at Indianapolis Colts | Sunday, October 12th, 2025 at 1:00pm ET | |
| Seattle Seahawks at Jacksonville Jaguars | Sunday, October 12th, 2025 at 1:00pm ET | |
| New England Patriots at New Orleans Saints | Sunday, October 12th, 2025 at 1:00pm ET | |
| Los Angeles Rams at Baltimore Ravens | Sunday, October 12th, 2025 at 1:00pm ET | |
| Tennessee Titans at Las Vegas Raiders | Sunday, October 12th, 2025 at 4:05pm ET | |
| San Francisco 49ers at Tampa Bay Buccaneers | Sunday, October 12th, 2025 at 4:25pm ET | |
| Cincinnati Bengals at Green Bay Packers | Sunday, October 12th, 2025 at 4:25pm ET | |
| Detroit Lions at Kansas City Chiefs | Sunday, October 12th, 2025 at 8:20pm ET | |
| Buffalo Bills at Atlanta Falcons | Monday, October 13th, 2025 at 7:15pm ET | |
| Chicago Bears at Washington Commanders | Monday, October 13th, 2025 at 8:15pm ET |
See the Full Season Schedule
