| Pittsburgh Steelers at Cincinnati Bengals | Thursday, October 16th, 2025 at 8:15pm ET |
Bye Week: BAL, BUF |
| Los Angeles Rams at Jacksonville Jaguars | Sunday, October 19th, 2025 at 9:30am ET | |
| Philadelphia Eagles at Minnesota Vikings | Sunday, October 19th, 2025 at 1:00pm ET | |
| Las Vegas Raiders at Kansas City Chiefs | Sunday, October 19th, 2025 at 1:00pm ET | |
| Miami Dolphins at Cleveland Browns | Sunday, October 19th, 2025 at 1:00pm ET | |
| Carolina Panthers at New York Jets | Sunday, October 19th, 2025 at 1:00pm ET | |
| New England Patriots at Tennessee Titans | Sunday, October 19th, 2025 at 1:00pm ET | |
| New Orleans Saints at Chicago Bears | Sunday, October 19th, 2025 at 1:00pm ET | |
| Indianapolis Colts at Los Angeles Chargers | Sunday, October 19th, 2025 at 4:05pm ET | |
| New York Giants at Denver Broncos | Sunday, October 19th, 2025 at 4:05pm ET | |
| Washington Commanders at Dallas Cowboys | Sunday, October 19th, 2025 at 4:25pm ET | |
| Green Bay Packers at Arizona Cardinals | Sunday, October 19th, 2025 at 4:25pm ET | |
| Atlanta Falcons at San Francisco 49ers | Sunday, October 19th, 2025 at 8:20pm ET | |
| Tampa Bay Buccaneers at Detroit Lions | Monday, October 20th, 2025 at 7:00pm ET | |
| Houston Texans at Seattle Seahawks | Monday, October 20th, 2025 at 10:00pm ET |
See the Full Season Schedule
