| Baltimore Ravens at Tampa Bay Buccaneers | Thursday, October 27th, 2022 at 8:15pm ET |
Bye Week: KC, LAC |
| Denver Broncos at Jacksonville Jaguars | Sunday, October 30th, 2022 at 9:30am ET | |
| Carolina Panthers at Atlanta Falcons | Sunday, October 30th, 2022 at 1:00pm ET | |
| Las Vegas Raiders at New Orleans Saints | Sunday, October 30th, 2022 at 1:00pm ET | |
| New England Patriots at New York Jets | Sunday, October 30th, 2022 at 1:00pm ET | |
| Pittsburgh Steelers at Philadelphia Eagles | Sunday, October 30th, 2022 at 1:00pm ET | |
| Miami Dolphins at Detroit Lions | Sunday, October 30th, 2022 at 1:00pm ET | |
| Chicago Bears at Dallas Cowboys | Sunday, October 30th, 2022 at 1:00pm ET | |
| Arizona Cardinals at Minnesota Vikings | Sunday, October 30th, 2022 at 1:00pm ET | |
| Tennessee Titans at Houston Texans | Sunday, October 30th, 2022 at 4:05pm ET | |
| San Francisco 49ers at Los Angeles Rams | Sunday, October 30th, 2022 at 4:25pm ET | |
| Washington Commanders at Indianapolis Colts | Sunday, October 30th, 2022 at 4:25pm ET | |
| New York Giants at Seattle Seahawks | Sunday, October 30th, 2022 at 4:25pm ET | |
| Green Bay Packers at Buffalo Bills | Sunday, October 30th, 2022 at 8:20pm ET | |
| Cincinnati Bengals at Cleveland Browns | Monday, October 31st, 2022 at 8:15pm ET |
See the Full Season Schedule
