| Minnesota Vikings at Los Angeles Chargers | Thursday, October 23rd, 2025 at 8:15pm ET |
Bye Week: ARI, DET, JAC, LV, SEA, LAR |
| New York Giants at Philadelphia Eagles | Sunday, October 26th, 2025 at 1:00pm ET | |
| Miami Dolphins at Atlanta Falcons | Sunday, October 26th, 2025 at 1:00pm ET | |
| Cleveland Browns at New England Patriots | Sunday, October 26th, 2025 at 1:00pm ET | |
| New York Jets at Cincinnati Bengals | Sunday, October 26th, 2025 at 1:00pm ET | |
| Buffalo Bills at Carolina Panthers | Sunday, October 26th, 2025 at 1:00pm ET | |
| San Francisco 49ers at Houston Texans | Sunday, October 26th, 2025 at 1:00pm ET | |
| Chicago Bears at Baltimore Ravens | Sunday, October 26th, 2025 at 1:00pm ET | |
| Tampa Bay Buccaneers at New Orleans Saints | Sunday, October 26th, 2025 at 4:05pm ET | |
| Dallas Cowboys at Denver Broncos | Sunday, October 26th, 2025 at 4:25pm ET | |
| Tennessee Titans at Indianapolis Colts | Sunday, October 26th, 2025 at 4:25pm ET | |
| Green Bay Packers at Pittsburgh Steelers | Sunday, October 26th, 2025 at 8:20pm ET | |
| Washington Commanders at Kansas City Chiefs | Monday, October 27th, 2025 at 8:15pm ET |
See the Full Season Schedule
