| Philadelphia Eagles at Houston Texans | Thursday, November 3rd, 2022 at 8:15pm ET |
Bye Week: CLE, DAL, DEN, NYG, PIT, SF |
| Buffalo Bills at New York Jets | Sunday, November 6th, 2022 at 1:00pm ET | |
| Los Angeles Chargers at Atlanta Falcons | Sunday, November 6th, 2022 at 1:00pm ET | |
| Carolina Panthers at Cincinnati Bengals | Sunday, November 6th, 2022 at 1:00pm ET | |
| Miami Dolphins at Chicago Bears | Sunday, November 6th, 2022 at 1:00pm ET | |
| Indianapolis Colts at New England Patriots | Sunday, November 6th, 2022 at 1:00pm ET | |
| Minnesota Vikings at Washington Commanders | Sunday, November 6th, 2022 at 1:00pm ET | |
| Las Vegas Raiders at Jacksonville Jaguars | Sunday, November 6th, 2022 at 1:00pm ET | |
| Green Bay Packers at Detroit Lions | Sunday, November 6th, 2022 at 1:00pm ET | |
| Seattle Seahawks at Arizona Cardinals | Sunday, November 6th, 2022 at 4:05pm ET | |
| Los Angeles Rams at Tampa Bay Buccaneers | Sunday, November 6th, 2022 at 4:25pm ET | |
| Tennessee Titans at Kansas City Chiefs | Sunday, November 6th, 2022 at 8:20pm ET | |
| Baltimore Ravens at New Orleans Saints | Monday, November 7th, 2022 at 8:15pm ET |
See the Full Season Schedule
