| ARI | This is a 3 star matchup. ARI has a neutral schedule in which RBs perform close to their average. | Kenyan Drake | Chase Edmonds | D.J. Foster |
| ATL | This is a 3 star matchup. ATL has a neutral schedule in which RBs perform close to their average. | Todd Gurley | Ito Smith | Brian Hill |
| BAL | This is a 3 star matchup. BAL has a neutral schedule in which RBs perform close to their average. | Mark Ingram II | Justice Hill | Gus Edwards |
| BUF | This is a 3 star matchup. BUF has a neutral schedule in which RBs perform close to their average. | Devin Singletary | T.J. Yeldon | Patrick DiMarco |
| CAR | This is a 3 star matchup. CAR has a neutral schedule in which RBs perform close to their average. | Christian McCaffrey | Mike Davis | Jordan Scarlett |
| CHI | This is a 3 star matchup. CHI has a neutral schedule in which RBs perform close to their average. | David Montgomery | Tarik Cohen | |
| CIN | This is a 3 star matchup. CIN has a neutral schedule in which RBs perform close to their average. | Joe Mixon | Giovani Bernard | Trayveon Williams |
| CLE | This is a 3 star matchup. CLE has a neutral schedule in which RBs perform close to their average. | Nick Chubb | Kareem Hunt | Dontrell Hilliard |
| DAL | This is a 3 star matchup. DAL has a neutral schedule in which RBs perform close to their average. | Ezekiel Elliott | Tony Pollard | Jamize Olawale |
| DEN | This is a 4 star matchup. DEN has a neutral schedule in which RBs perform close to their average. | Phillip Lindsay | Melvin Gordon | Royce Freeman |
| DET | This is a 3 star matchup. DET has a neutral schedule in which RBs perform close to their average. | Kerryon Johnson | Ty Johnson | Nick Bawden |
| GB | This is a 3 star matchup. GB has a neutral schedule in which RBs perform close to their average. | Aaron Jones | Jamaal Williams | Dexter Williams |
| HOU | This is a 3 star matchup. HOU has a neutral schedule in which RBs perform close to their average. | David Johnson | Duke Johnson | Karan Higdon |
| IND | This is a 3 star matchup. IND has a neutral schedule in which RBs perform close to their average. | Marlon Mack | Nyheim Hines | Jordan Wilkins |
| JAC | This is a 3 star matchup. JAC has a neutral schedule in which RBs perform close to their average. | Leonard Fournette | Ryquell Armstead | Devine Ozigbo |
| KC | This is a 3 star matchup. KC has a neutral schedule in which RBs perform close to their average. | Damien Williams | Darwin Thompson | Elijah McGuire |
| MIA | This is a 3 star matchup. MIA has a neutral schedule in which RBs perform close to their average. | Jordan Howard | Kalen Ballage | Myles Gaskin |
| MIN | This is a 3 star matchup. MIN has a neutral schedule in which RBs perform close to their average. | Dalvin Cook | Alexander Mattison | Ameer Abdullah |
| NE | This is a 3 star matchup. NE has a neutral schedule in which RBs perform close to their average. | Sony Michel | James White | Damien Harris |
| NO | This is a 3 star matchup. NO has a neutral schedule in which RBs perform close to their average. | Alvin Kamara | Latavius Murray | Dwayne Washington |
| NYG | This is a 3 star matchup. NYG has a neutral schedule in which RBs perform close to their average. | Saquon Barkley | Dion Lewis | Wayne Gallman |
| NYJ | This is a 3 star matchup. NYJ has a neutral schedule in which RBs perform close to their average. | Le'Veon Bell | Josh Adams | Trenton Cannon |
| LV | This is a 0 star matchup. LV has a tough schedule in which RBs perform worse than their average. | Josh Jacobs | Jalen Richard | Rod Smith |
| PHI | This is a 3 star matchup. PHI has a neutral schedule in which RBs perform close to their average. | Miles Sanders | Elijah Holyfield | Boston Scott |
| PIT | This is a 3 star matchup. PIT has a neutral schedule in which RBs perform close to their average. | James Conner | Jaylen Samuels | Benny Snell Jr. |
| LAC | This is a 3 star matchup. LAC has a neutral schedule in which RBs perform close to their average. | Austin Ekeler | Justin Jackson | Troymaine Pope |
| SEA | This is a 3 star matchup. SEA has a neutral schedule in which RBs perform close to their average. | Chris Carson | Rashaad Penny | C.J. Prosise |
| SF | This is a 3 star matchup. SF has a neutral schedule in which RBs perform close to their average. | Tevin Coleman | Matt Breida | Raheem Mostert |
| LAR | This is a 3 star matchup. LAR has a neutral schedule in which RBs perform close to their average. | Darrell Henderson | Malcolm Brown | John Kelly |
| TB | This is a 3 star matchup. TB has a neutral schedule in which RBs perform close to their average. | Ronald Jones II | Dare Ogunbowale | T.J. Logan |
| TEN | This is a 3 star matchup. TEN has a neutral schedule in which RBs perform close to their average. | Derrick Henry | David Fluellen | Dalyn Dawkins |
| WAS | This is a 3 star matchup. WAS has a neutral schedule in which RBs perform close to their average. | Derrius Guice | Peyton Barber | Adrian Peterson |
