After sustaining a foot injury on Sunday, an MRI revealed a foot sprain that will keep the third-year corner from action for at least a month. Emmanuel Moseley is currently in the lead to replace Witherspoon, not Jason Verrett who struggled on Sunday in his return from an Achilles tear. (Matt Maiocco on Twitter)
Witherspoon started his 2019 campaign on a mission to bounce back from a mediocre sophomore year. He's played a key role in the 49ers secondary and while his loss isn't crushing to the 49ers D/ST value, it does hurt slightly. The team gets an early Week 4 bye so they may only lose Witherspoon for 3-4 games. With a stout defensive line and linebacking corps, the team should continue to cause issues for opposing QBs and RBs.