Christian McCaffrey Week 6 Outlook - 49ers at Buccaneers

By Ellis Johnson (FantasyPros), Tue, Oct 7th 2025, 10:43pm EDT

It seems kind of weird to write about CMC as the second-highest-ranked RB on the week. This isn't because he doesn't deserve to be here; it's more about how his production is coming. This season, CMC is a WR1 that moonlights as a fantasy RB2. Together, you get one of the best players in all of fantasy. What I mean by this is that his 387 receiving yards are 117 more than the next highest RB. It also puts him sixth across all positions in receiving yards and third in receptions. This week, he faces a Bucs team that is stout on the ground but is vulnerable to receiving backs. That's perfect for CMC to have another incredible performance in Week 6.