Davante Adams Week 10 Outlook - Rams at 49ers

By Ellis Johnson (FantasyPros), Tue, Nov 4th 2025, 8:03pm EST

Peanut butter and jelly, brushing your teeth in the shower, Davante Adams and Matthew Stafford; something just makes sense. With how unpredictable the NFL can be, it's great when player combinations that should be great actually come to fruition. This is exactly what is happening with Stafford and Adams. Averaging 2.5 red zone targets per game, Adams is leading the league with 20. The second-highest in red zone looks is Amon-Ra St. Brown with 14. Adams also holds contingent upside if Puka Nacua misses time. With Nacua missing half of last game with a chest injury, his status is uncertain for Week 10. Either way, Adams is one of the few receivers with multi-touchdown upside on any given week. Especially against a beat-up 49ers secondary, Adams is a WR1 once again this week.