Brock Purdy Week 16 Outlook - 49ers at Colts

By Derek Brown (FantasyPros), Thu, Dec 18th 2025, 1:35pm EST

Since his Week 11 return, Brock Purdy has two QB1 weekly finishes (QB3, QB6). Since Week 11, among 37 qualifying quarterbacks, Purdy has ranked 15th in passing yards per game, 11th in highly accurate throw rate, 13th in catchable target rate, and eighth in passing touchdowns (tied). Purdy could spit out QB1 numbers again this week. Since Week 11, Indy has allowed the second-most passing yards per game and the tenth-most yards per attempt despite allowing the eighth-lowest adjusted completion rate. During that span they have also ranked 17th in pressure rate, so Purdy should have time to find open receivers this week.