Shedeur Sanders Week 16 Outlook - Bills at Browns

By Derek Brown (FantasyPros), Thu, Dec 18th 2025, 1:35pm EST

After a wonderful performance against the Titans in Week 14, Shedeur Sanders came crashing back to earth last week with a 51.4% completion rate, 177 passing yards, zero passing touchdowns, and three interceptions (QB31 for the week). Since Week 12, among 33 qualifying passers, Sanders has ranked 13th in yards per attempt, 15th in hero throw rate, 24th in highly accurate throw rate, and 30th in catchable target rate. This week, he's a QB2 that is best left on the bench. Since Week 11, Buffalo has allowed the fifth-fewest passing yards per game, the eighth-lowest yards per attempt, the fourth-lowest CPOE, and they have ranked 16th in success rate per dropback. Sanders should at least have time in the pocket this week. Since Week 11, Buffalo has had the second-lowest pressure rate.