San Francisco 49ers Fantasy Football Outlook (2026)

By Andrew Erickson (FantasyPros), Wed, Jun 3rd 2026, 11:33am EDT

They open the season versus the Rams in Australia, but then it's smooth sailing from Weeks 2-3 (vs MIA and ARI at home). If you don't draft the Niners, they will be a priority waiver wire addition ahead of Week 2. Tied for the second-fewest interceptions in 2025 after being completely gutted by injuries.