Keaton Mitchell Week 1 Outlook - Cardinals at Chargers

By Derek Brown (FantasyPros), Sun, Sep 13th 2026, 12:44pm EDT

Keaton Mitchell will be Omarion Hampton's running mate in the backfield in 2026. We'll still have to see how much usage/volume he'll see on a weekly basis, but he could negate those concerns with his big-play ability as a deep league flex in Week 1. Last season, he had only 68 touches, but he had a 10.2% explosive run rate and a respectable 1.37 yards per route run. Last year, Arizona allowed the third-highest explosive run rate, the fifth-highest rushing success rate, and the 12th-most yards before contact per attempt.