Here are rankings from our analysts for Week 5 of the fantasy football season. You can find our expert consensus fantasy football rankings for the week here. And you can also sync your fantasy football league for free using our My Playbook tool for custom advice, rankings, and analysis.
- Fantasy Football Start/Sit Rankings & Advice: Quarterback
- Fantasy Football Start/Sit Rankings & Advice: Wide Receiver
- Fantasy Football Start/Sit Rankings & Advice: Tight End
- Fantasy Football Start/Sit Rankings & Advice: Defense
- Fantasy Football Start/Sit Rankings & Advice: Kicker
Check out all of our Week 5 fantasy football content 
If you want to dive deeper into fantasy football, be sure to check out our award-winning slate of Fantasy Football Tools as you navigate your season. From our Start/Sit Assistant – which provides your optimal lineup, based on accurate consensus projections – to our Waiver Wire Assistant – which allows you to quickly see which available players will improve your team and by how much – we’ve got you covered this fantasy football season.
Fantasy Football Week 5 Rankings & Start/Sit Advice
Week 5 Player Notes & Start/Sit Advice
Clyde Edwards-Helaire (KC) vs. LV: Chiefs -7 | 51 O/U
- A guy doesn’t need to be good to have 325 yards and five touchdowns if he’s on an offense that’s No. 1 in total EPA per play (0.211).
- Edwards-Helaire could benefit from a run-heavy game script as a heavy home favorite (at FanDuel).
Jeff Wilson (SF) at CAR: 49ers -6.5 | 39.5 O/U
- No. 1 RB Elijah Mitchell (knee, IR) is out, and Mitchell is 48-233-1 rushing and 5-50-0 receiving on five targets over the past three weeks starting in his place.
- In his 13 career games with 15-plus opportunities, Wilson has averaged 16.4 FPPG (per FTN).
Damien Harris (NE) vs. DET: Patriots -3 | 45.5 O/U
- Especially with either backup Brian Hoyer (concussion) or third-string rookie Bailey Zappe at quarterback, the Patriots are likely to run heavily as home favorites (per BetMGM).
- Harris has a respectable 275 yards and three touchdowns and an elevated floor with 12-plus opportunities in each game.
- The Lions defense is No. 32 in both rush EPA (0.163) and rush DVOA (18.5%) and is at a significant matchup advantage in our unit power rankings.
| Rank | RBs | Opp Defense | DL Rank | LBs Rank | RB-DL Edge | RB-LB Edge |
|---|---|---|---|---|---|---|
| 10 | NE | DET | 28 | 31 | 18 | 21 |
Alvin Kamara (NO) vs. SEA: Saints -5.5 | 46 O/U
- Kamara (ribs) was a surprise late inactive last week, which makes me optimistic that he’ll play this week.
- In Week 1, Kamara suffered an injury, and he missed Weeks 2 & 4 because of the injury — but in Week 3 he had 15 carries and seven targets.
- The Seahawks defense is No. 4 in most fantasy points allowed to running backs (26.0 FPPG).
Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | SoundCloud | iHeartRadio
If you want to dive deeper into fantasy football, be sure to check out our award-winning slate of Fantasy Football Tools as you navigate your season. From our Start/Sit Assistant – which provides your optimal lineup, based on accurate consensus projections – to our Waiver Wire Assistant – which allows you to quickly see which available players will improve your team and by how much – we’ve got you covered this fantasy football season.
