Tonight’s MLB DFS main slate has 12 games starting at 7:05 p.m. ET at DraftKings and FanDuel. The suggested pick ’em choices from Sleeper and Underdog are from the 12-game slate.
Check out our best picks on the MLB Underdog Cheat Sheet 
Today’s MLB DFS & Player Props Picks
Friday’s Starting Pitcher Rankings
Hunter Brown (HOU) vs. CIN
Hunter Brown is pitching at a Cy Young Award caliber this season. According to FanGraphs, he has had the following stats in seven starts spanning 43 innings.
- 1.67 ERA
- 3.03 xERA
- 2.56 xFIP
- 2.71 SIERA
- 0.88 WHIP
- Five wins
- Seven quality starts
- 6.3 BB%
- 31.0 K%
- 49.5 GB%
- 12.1 SwStr%
- 29.6 CSW%
- 111 stuff+
- 107 location+
- 117 pitching+
Brown has a favorable matchup and excellent betting info tonight. The Reds are 21st in wRC+ (96) with a 22.8 K% versus righties and tied for eighth in wRC+ (109) with a 23.8 K% on the road this season. Thus, the Astros are -175, and the game’s total is a pitcher-friendly 7.5 runs.
Luis Castillo (SEA) vs. TOR
Luis Castillo’s 2025 starts are mixed. However, he’s superb at home. In 20 starts spanning 120 innings at home since last year, Castillo has had a 2.85 ERA, 3.39 xFIP, 1.06 WHIP, 5.4 BB% and 26.3 K%. He’s pitched at least five innings and yielded two runs or fewer in four home starts this year, including throwing back-to-back scoreless starts in his two previous turns at home.
Castillo’s matchup against the Blue Jays is tasty. Toronto is 27th in wRC+ (86) with a 19.1 K% versus righties and tied for 27th in wRC+ (75) with a 20.2 K% on the road this season. So, the Mariners are -136, and the game’s total is 7.5 runs.
Clay Holmes (NYM) vs. CHC
Clay Holmes has successfully transitioned from relieving to starting. The righty’s 2.99 xERA this year is the lowest among tonight’s probable starters. Holmes also has a 2.95 ERA, 3.35 xFIP, 3.49 SIERA, 1.28 WHIP, 8.3 BB%, 25.0 K% and 51.5 GB%. His pitch-modeling data is also outstanding, namely his 100 stuff+, 106 location+ and 110 pitching+.
Holmes has a tricky matchup tonight. Yet, he’s talented enough to overcome the matchup, as evidenced by the Mets listing at -155 and the game’s total at 8.0 runs. Holmes is an intriguing GPP option.
Suggested Lineup Stacks
Sutter Health Park has the second-highest park factor for runs (121) and the ninth-highest park factor for homers (119) this year. It’s served as a launching pad. Will Warren isn’t built to tame an opposing offense in a hitter-friendly venue. He has a 5.65 ERA this season in seven starts and a 7.71 ERA in 51.1 innings since reaching the Majors last year. Additionally, Warren has surrendered a .396 wOBA to 143 lefties and a .361 wOBA to 98 righties in his young big-league career.
- Home (Coors Field)
- Game Total/Moneyline: 10.5 Runs/COL +138
Coors Field is MLB’s most hitter-friendly ballpark over the last three full seasons. Even though it hasn’t warmed up yet, it’s tied for the fourth-highest park factor for runs (114) this season. Offense is frequently plentiful in Colorado. Colorado’s lineup isn’t impressive, but they can feast on Randy Vasquez. San Diego’s starting pitcher has an unsightly 6.11 xERA, 6.63 xFIP, 6.68 SIERA and 1.67 WHIP in seven starts spanning 32.1 innings this year. Remarkably, Vasquez has 24 walks and only 13 strikeouts this year. The Rockies should tee off on him.
Core Studs
- Brent Rooker has had a .338 OBP, .246 ISO and 139 wRC+ versus righties since 2023.
- Michael Toglia has hit three homers with a .375 OBP, .273 ISO and 146 wRC+ in 48 plate appearances against righties at home this year.
- In 38 games and 160 plate appearances this year, Tyler Soderstrom has nine homers, 24 runs, 25 RBIs, two stolen bases, a .350 OBP, .228 ISO, 147 wRC+ and .392 xwOBA.
Value Plays/Punts
- In 502 plate appearances against righties at home since 2023, Ryan McMahon has hit 17 homers with a .327 OBP, .176 ISO and .323 wOBA.
- In 80 plate appearances this year, Daniel Schneemann has five homers, 13 runs, 11 RBIs, a .367 OBP, .286 ISO, 167 wRC+ and .390 xwOBA.
- J.P. Crawford has three homers, 18 runs, 17 RBIs, two stolen bases, a .408 OBP, .102 ISO, 145 wRC+ and .374 xwOBA in 144 plate appearances this year.
Friday’s Top 3 Sleeper and Underdog Player Props
Check out our best picks on the MLB Underdog Cheat Sheet
Michael Toglia: 1.5 Hits + Runs + RBIs – Higher (Sleeper) (1.71x)
Michael Toglia: 1.5 Hits + Runs + RBIs – Higher (Underdog)
Toglia has exceeded 1.5 hits plus runs and RBIs in eight of 17 starts at home this year. However, he has a juicy matchup tonight. Vasquez has ceded a .343 batting average, .413 OBP and .498 slugging to lefties since last season, and his ERA estimators this season are horrendous. So, Toglia should have ample run-production opportunities tonight.
Hunter Brown: 17.5 Pitching Outs – Higher (Sleeper) (1.36x)
Hunter Brown: 17.5 Pitching Outs – Higher (Underdog) (0.74x)
Brown has tallied at least 18 outs in all seven of his starts this year. He also recorded at least 18 outs in his final two starts in the 2024 regular season and six of his final seven.
Luis Castillo: 2.5 Earned Runs – Lower (Sleeper) (1.65x)
Luis Castillo: 2.5 Earned Runs – Lower (Underdog) (0.91x)
Castillo has allowed fewer than 2.5 earned runs in back-to-back starts and five of his seven starts in 2025. He’s also allowed fewer than 2.5 earned runs in all four of his starts at home this year.
Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.
