Josh Shepardson | Tue, Apr 21st 2026, 7:05am EDT

MLB DFS Picks & Underdog Player Props: Tuesday (4/21)

Tuesday’s MLB DFS main slate at DraftKings and FanDuel has nine games, starting at 7:10 p.m. ET. The following pick ’em selections from Underdog are also from those nine games.

Tuesday’s Top MLB DFS Picks & Player Props

Tuesday’s Starting Pitcher Rankings (4/21)

Yoshinobu Yamamoto (SP – LAD) at Los Angeles Dodgers

Yoshinobu Yamamoto is pitching well this season, and he’s a road warrior. According to FanGraphs, in 111.2 innings pitched on the road since last year, Yamamoto has spun a 2.10 ERA, 2.95 xFIP, 0.90 WHIP, 7.7 BB% and 28.8 K%.

LA’s righty has a tasty matchup tonight. The Giants are 27th in wRC+ (81) with a 20.7 K% versus righties and 28th in wRC+ (72) with a 21.8 K% at home this year. Thus, the Dodgers are -185 favorites, and the game’s total is a pitcher-friendly 7.0 runs. Yamamoto is the top pitcher in all game types at both DFS providers.

Shota Imanaga (SP – CHC) vs. Philadelphia Phillies

Shota Imanaga is thriving. In four starts spanning 22 innings this year, the lefty has logged the following statistics.

1 win
2 quality starts
2.45 ERA
2.55 xERA
2.49 xFIP
2.28 SIERA
0.77 WHIP
6.1 BB%
37.8 K%
16.4 SwStr%
29.6 CSW%
101 stuff+
110 location+
107 pitching+

Imanaga has a drool-inducing matchup and adequate betting info. The Phillies are dead last in wRC+ (59) with a 23.6 K% versus lefties and 21st in wRC+ (83) with a 23.5 K% on the road this season. In addition, the Cubs are -120 favorites, and the game’s total is 8.5 runs.

Kris Bubic (SP – KC) vs. Baltimore Orioles

Kris Bubic is strictly an upside-chasing GPP selection. The game’s total is a hitter-friendly 9.0 runs, but the Royals are -130 favorites. Furthermore, the Orioles are tied for 10th in wRC+ (110) against lefties in 2026, but they have a 25.7 K% versus lefties, and their projected starters have a track record of striking out at a high clip against southpaws. Baltimore is also 25th in wRC+ (78) with a 28.6 K% on the road.

Bubic is built for a ceiling outcome. In four starts spanning 22.2 innings, Bubic has a 29.2 K%, with a 13.2 SwStr%, 28.7 CSW%, 91 stuff+, 106 location+ and 101 pitching+. He has struck out four, eight, 11 and three batters in his four turns, and the Orioles are the type of lineup to coax a ceiling strikeout performance from Bubic on Tuesday night.

Suggested Lineup Stacks

Home (Angel Stadium)
Game Total/Moneyline: 9.5 Runs/LAA -110

Patrick Corbin‘s 7.93 xERA is the second-highest mark among tonight’s probable starting pitchers, and his 4.66 ERA, 4.35 xFIP and 1.86 HR/9 are enticing numbers to stack against as well. Furthermore, he’s coughed up a .342 wOBA to right-handed batters since 2024, and all nine of the projected starters for the Angels are right-handed batters or switch-hitters.

Home (T-Mobile Park)
Game Total/Moneyline: 7.5 Runs/SEA -170

Jacob Lopez is on the struggle bus this year. In four starts spanning 18.1 innings, Lopez has a 6.38 ERA, 4.00 xERA, 6.33 xFIP, 6.20 SIERA, 1.96 WHIP, 18.9 BB% and 17.8 K%. It’s unfathomable that he has a higher walk than strikeout rate through four turns. Moreover, Lopez hasn’t found success away from his hitter-friendly home ballpark. Instead, he has a 5.81 ERA and 4.99 xFIP in 57.1 innings on the road since last year.

Core Studs

Zach Neto has launched 13 long-balls with a .369 OBP, .241 ISO, .384 wOBA and 150 wRC+ in 249 plate appearances against lefties since 2024.
Jo Adell has mashed 18 taters with a .369 OBP, .241 ISO, .395 wOBA and 157 wRC+ in 240 plate appearances against lefties since 2024.
Mike Trout has belted seven bombs with 22 runs, 16 RBI, three stolen bases, a .415 OBP, .309 ISO, .416 wOBA and 166 wRC+ in 106 plate appearances this year.

Value Plays/Punts

Mitch Garver is a DraftKings-specific punt, where gamers must use a catcher, and he’s only $100 above the minimum salary. He has hit 13 home runs with a .325 OBP, .182 ISO, .319 wOBA and 113 wRC+ in 323 plate appearances against lefties since 2024.
Vinnie Pasquantino has hit 43 homers with a .333 OBP, .209 ISO, .346 wOBA and 121 wRC+ in 1,013 plate appearances against righties since 2024, and he’s underpriced for a No. 3 hitter of his caliber because of a slow start to his 2026 campaign.
Jeff McNeil has sat atop the order for the A’s in three of his last four starts, and he’s an above-average hitter against righties, with a 107 wRC+ against them since 2024. The total package he offers is quite appealing at his punt salary.

Tuesday’s Top 3 Underdog Player Props

Check out our best picks on the MLB Underdog Cheat Sheet

Kumar Rocker (SP – TEX): 5.5 Strikeouts — Lower (0.81x Payout)

Kumar Rocker‘s 20.9 K% through three starts is fine, but his pitch-modeling data, which includes 93 stuff+, 96 location+ and 90 pitching+, is unimpressive, and his 11.9 SwStr% is OK, but his 22.7 CSW% is lousy. Rocker struck out six batters in his most recent start. However, he had only three and five strikeouts in his first two turns, and he’s cleared 5.5 strikeouts only four times in 17 starts since last season.

Kris Bubic (SP – KC): 16.5 Outs — Higher

Bubic has tallied 22.2 innings (68 outs) in four starts, for an average of 17 outs per start. He’s exceeded 16.5 outs in two of four starts, including two of three at home this season.

Corey Seager (SS – TEX): 1.5 Hits + Runs + RBI — Higher (0.86x Payout)

Corey Seager is a monster with the platoon advantage at home. The left-handed-hitting shortstop has 87 hits, a .297 batting average, .401 OBP, .256 ISO, .397 wOBA and 164 wRC+ in 349 plate appearances against righties at home since 2024.

Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.

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