Wednesday’s MLB DFS main slate at FanDuel features nine games and starts at 6:40 p.m. ET. The main slate at DraftKings includes only six games, starting at 7:05 p.m. ET. The touted Underdog pick’em choices are also from the night’s nine games.
Wednesday’s Top MLB DFS Picks & Player Props
Wednesday’s Starting Pitcher Rankings (5/20)
According to FanGraphs, among 116 pitchers with at least 40 innings pitched this season, Shohei Ohtani is first in ERA (0.82), second in xERA (2.32), 13th in xFIP (3.04), ninth in SIERA (2.94), third in WHIP (0.82) and tied for 10th in strikeout rate (29.2 K%).
Ohtani also has three wins, seven quality starts, a 14.4% SwStr%, 32.2% CSW%, 115 stuff+, 100 location+ and 113 pitching+ in seven starts spanning 44 innings this season.
The two-way superstar has a plus-matchup and positive betting info. The Padres are 22nd in wRC+ (94) with a 23% strikeout rate versus righties and 25th in wRC+ (91) with a 21.9 K% strikeout rate at home in 2026. Thus, the Dodgers are -175 favorites, and the game’s total is seven runs.
The Blue Jays are 23rd in wRC+ (91) with an 18.5% strikeout rate versus righties and tied for 27th in wRC+ (82) with an 18% strikeout rate on the road this year.
The Yankees are -160 favorites, and the game’s total is eight runs. Cam Schlittler‘s context is a little less DFS-friendly than Ohtani’s, which is why New York’s ace is behind Los Angeles’s ace.
Schlittler has posted numbers that are on par with Ohtani’s. In 10 starts, totaling 60 innings, in 2026, Schlittler has the following numbers.
- 6 wins
- 6 quality starts
- 1.35 ERA
- 2.60 xERA
- 2.57 xFIP
- 2.69 SIERA
- 0.78 WHIP
- 4.9% walk rate
- 30.1% strikeout rate
- 14.7% SwStr%
- 28.6% CSW%
- 113 stuff+
- 108 location+
- 117 pitching+
Schlittler can rival Ohtani for the highest-scoring pitcher on tonight’s DFS slate.
Kyle Harrison has a brutal matchup tonight. The Cubs are third in wRC+ (120) with a 21.3% strikeout rate versus lefties and second in wRC+ (126) with an 18.7% strikeout rate at home this season. Yet, the Brewers are listed at even odds, and the game’s total is a pitcher-friendly 6.5 runs.
Harrison has earned the respect of bettors by dazzling this season. In eight starts spanning 38.2 innings, the lefty has posted the following numbers:
- 4 wins
- 2 quality starts
- 2.09 ERA
- 3.32 xERA
- 3.11 xFIP
- 3.13 SIERA
- 1.19 WHIP
- 8.1% walk rate
- 30% strikeout rate
- 14.2% SwStr%
- 29.9% CSW%
- 105 stuff+
- 114 location+
- 115 pitching+
Harrison is an unappealing selection at FanDuel. However, he’s an excellent pick in all game types as an SP2 at DraftKings.
Suggested Lineup Stacks
The game’s total is unlikely to cause gamers to flock to stacking the Brewers. Still, Edward Cabrera is an unimposing matchup. He has a 4.06 ERA, 4.37 xERA, 3.87 xFIP, 4.10 SIERA and 1.31 WHIP in nine starts this season.
Meanwhile, Milwaukee’s projected lineup features six players with at least a 108 wRC+ against righties since 2024. The Brewers have the caliber of hitters and lineup depth to pay off for gamers who stack them.
Jack Kochanowicz is a punching bag. He has a 4.56 ERA, 5.52 xERA, 4.66 xFIP, 4.83 SIERA, 1.36 WHIP, 11% walk rate and 15% strikeout rate in nine starts.
The 25-year-old righty has allowed a .330 wOBA to righties and a .373 wOBA to lefties since 2025. In addition, the Angels have the fifth-highest bullpen ERA (4.93) this season.
Core Studs
- Carlos Cortes has swatted eight homers with a .361 on-base percentage (OBP), .225 ISO, .386 wOBA and 145 wRC+ in 205 plate appearances against righties since reaching the Majors last year.
- Brice Turang has belted 28 bombs with a .353 OBP, .150 ISO, .341 wOBA and 119 wRC+ in 1,092 plate appearances against righties since 2024.
- Christian Yelich has mashed 34 taters with a .374 OBP, .218 ISO, .375 wOBA and 143 wRC+ in 699 plate appearances against righties since 2024.
Value Plays/Punts
- Henry Bolte had nine homers, a .430 OBP, .232 ISO and .435 wOBA in 244 career plate appearances against righties in Triple-A.
- Yoan Moncada has hit 15 homers with a .344 OBP, .199 ISO, .344 wOBA and 120 wRC+ in 401 plate appearances against righties since 2024.
- Andrew Vaughn isn’t a lock to be in Milwaukee’s lineup, but Sal Frelick hasn’t done much to warrant retaining an everyday role, and the Brewers have the flexibility to get Vaughn and Jake Bauers into the lineup together. In 193 plate appearances against righties since the Brewers acquired Vaughn in a trade, he’s hit eight homers with a .311 OBP, .192 ISO, .325 wOBA and 109 wRC+. Vaughn is a bargain at DraftKings if he’s in the lineup.
Wednesday’s Top 3 Underdog Player Props
Check out our best picks on the MLB Underdog Cheat Sheet 
Brice Turang has recorded 47 hits, including seven homers, 39 runs, 29 RBIs, a .292 batting average, .413 OBP, .205 ISO, .402 wOBA and 158 wRC+ in 43 games and 198 plate appearances this year.
Injuries have limited Christian Yelich to only 19 games and 75 plate appearances this year. Still, he’s amassed 20 hits, 13 runs, 13 RBIs, a .290 batting average, .347 OBP, .217 ISO, .365 wOBA and 133 wRC+ this year.
Oneil Cruz has rattled off 51 hits (including 10 homers), 35 runs, 33 RBIs, a .264 batting average, .330 OBP, .202 ISO, .349 wOBA and 120 wRC+ in 46 games and 212 plate appearances this year.
Conversely, Michael McGreevy has coughed up 78 hits, a .270 batting average, .319 OBP and .460 slugging rate to 313 left-handed batters since last season.
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Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.
