Dennis Santana struck out no batters while allowing one walk and no hits in a scoreless inning to earn the save in Wednesday's victory against the Pirates.

Fantasy Impact: This performance marks a positive turn for Santana, who had struggled to find consistency in his three outings prior to Wednesday. While his strikeout rate remains impressive at 8.10 K/9, his high walk rate and elevated BABIP suggest that he may not be as reliable moving forward. Fantasy managers should monitor his usage closely, as this save could lead to more opportunities if he can tighten up his command.

Paul Skenes allowed no earned runs on three hits and zero walks while striking out six over seven innings in Wednesday's win against the Rays.

Fantasy Impact: This stellar performance marks a strong start to Skenes's season, showcasing his ability to limit baserunners and generate strikeouts, as evidenced by his impressive 9.49 K/9 rate. With a 1.46 ERA and a 0.65 WHIP, Skenes is emerging as a reliable option for fantasy managers looking for strikeout potential and stability in their rotation. His ability to maintain control, as shown by his zero walks allowed in this outing, further enhances his appeal moving forward.

Oneil Cruz went 2-for-4 in win over the Rays with a home run, two RBI, one run scored, and one stolen base.

Fantasy Impact: This performance marks a positive sign for Cruz, who has struggled early in the season with a .261 batting average across six games. His ability to contribute both with power and speed, as evidenced by his six stolen bases, suggests he has the potential to be a valuable asset in fantasy lineups moving forward, especially if he can improve his consistency at the plate.

Pirates OF Bryan Reynolds has been dealing with right triceps soreness that impacts his throwing, senior director of sports medicine Todd Tomczyk said Wednesday, per Noah Hiles of the Pittsburgh Post-Gazette. The issue explains Reynolds' recent usage primarily at designated hitter, though his hitting is reportedly unaffected. (Source: Noah Hiles)

Fantasy Impact: The triceps issue only affects Reynolds' throwing, allowing him to stay in the lineup as DH without impacting his offensive production. While his fantasy value is largely unchanged, his move to DH has recently pushed Andrew McCutchen out of the lineup.

Enmanuel Valdez is not in the starting lineup for the Pirates against the Rays.

Fantasy Impact: Valdez sits Wednesday after starting the Pirates' previous game.

Joey Bart is not in the starting lineup for the Pirates against the Rays.

Fantasy Impact: Bart sits Wednesday after starting the Pirates' previous game.

Endy Rodríguez is starting at catche for the Pirates against the Rays.

Fantasy Impact: He will hit out of the seventh spot in the lineup Wednesday.

Adam Frazier is starting at second base for the Pirates against the Rays.

Fantasy Impact: He will hit out of the first spot in the lineup Wednesday.

Joey Wentz pitched one inning without allowing a hit or a walk in Tuesday's loss to the Rays.

Fantasy Impact: While his performance was solid, the lack of strikeouts and the team's overall struggles may limit his fantasy appeal. With a 2.25 ERA and a low BABIP, Wentz shows potential, but his inability to generate strikeouts and the absence of saves or holds keep him off the radar for most fantasy leagues.

Caleb Ferguson allowed one hit and one walk in a scoreless inning during Tuesday's loss to the Rays.

Fantasy Impact: While he maintained a perfect ERA this season, his lack of strikeouts and a concerning strikeout-to-walk ratio suggest he may not be a reliable option for fantasy managers looking for saves or holds. With a WHIP of 1.25 and a FIP of 5.26, Ferguson's effectiveness could be in question moving forward, making him a risky add in deeper leagues.

Justin Lawrence struck out two batters while allowing no hits and one walk in a scoreless appearance against the Pirates.

Fantasy Impact: Despite the loss, Lawrence's impressive 15.0 K/9 and solid 3.00 ERA indicate he has the potential to be a valuable asset in fantasy leagues. However, his lack of saves and a blown save earlier this season may limit his immediate value, making him more of a speculative add for teams seeking strikeouts rather than a reliable closer option.

Thomas Harrington allowed six earned runs on seven hits and four walks while striking out two over 4.0 innings in Tuesday's loss to the Rays.

Fantasy Impact: This outing only adds to his troubling season stats, as he now holds a 13.50 ERA and a 2.75 WHIP after two starts. With a strikeout-to-walk ratio of 0.50 and a concerning 8.51 FIP, Harrington's fantasy value is rapidly diminishing, making him a risky option moving forward.

Isiah Kiner-Falefa went 1-for-3 in loss to the Rays with no runs, RBI, or stolen bases.

Fantasy Impact: Despite the lackluster performance in this game, Kiner-Falefa has shown some promise early in the season with a .333 batting average and four stolen bases across six games. However, his inability to drive in runs or score in this outing may raise concerns about his overall impact on fantasy rosters moving forward. Owners should monitor his performance closely, as he has the potential to contribute in steals but needs to improve his consistency at the plate.

Jared Triolo went 1-for-3 in loss to the Rays with no runs, no RBI, and one strikeout.

Fantasy Impact: Triolo's performance continues to highlight his struggles at the plate, as he now holds a dismal .100 batting average and has yet to drive in a run this season. With a 0.300 strikeout rate and a lack of walks, his fantasy value is plummeting, making him a risky option in any lineup until he can find his footing.

Ke'Bryan Hayes went 2-for-4 in the loss to the Rays, failing to drive in any runs.

Fantasy Impact: Despite the two hits, his season-long struggles continue, as he holds a disappointing .200 batting average with no RBIs through six games. Fantasy managers should be cautious, as his lack of power and low wOBA of .176 indicate limited upside at this point in the season.

Tommy Pham went 0-for-4 in loss to the Rays with two strikeouts.

Fantasy Impact: Pham's ongoing struggles at the plate continue to raise concerns for fantasy managers, as he now holds a dismal .095 batting average and has yet to drive in a run this season. With a strikeout rate nearing 35%, his playing time could be at risk if he doesn't turn things around soon. Fantasy managers should consider looking for alternatives as Pham's current form offers little upside.

Jack Suwinski went 0-for-4 in loss to the Rays with three strikeouts.

Fantasy Impact: His ongoing struggles continue to weigh down his fantasy value, as he now holds a dismal .133 batting average and a 0.353 strikeout rate this season. With no home runs and limited production, fantasy managers should consider benching him until he shows signs of improvement.

The Pirates have designated Jason Delay for assignment. (Source: Pirates on Twitter )

Fantasy Impact: Delay will lose his spot on the 40-man roster to Thomas Harrington. He will hit the waiver wire.

Carmen Mlodzinski allowed four runs on seven hits across 3 2/3 innings with four strikeouts and two walks on Monday against the Rays.

Fantasy Impact: Mlodzinski tossed three scoreless innings before it got out of hand in the fourth inning. He will remain off the fantasy radar when he takes on the Cardinals in his next start.

The Pirates transferred Jared Jones to the 60-day injured list.

Fantasy Impact: Jones remains on track to be sidelined until at least June.