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Isaac Guerendo

Isaac Guerendo

RB - San Francisco 49ers

Height: 6' Weight: 221 lbsAge: 24College: Louisville

2024 Outlook

Strength of Schedule
RB Rank: 27th (hard)
Draft Rank (ECR) #302
Best / Worst #236 / #332
ADP #230

Roster %

Expert Note
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An underrated addition/invitee to the NFL Combine, Isaac Guerendo was way off the radar until he blazed a 4.33 40-yard dash and jumped a 41.5″ vertical/ 129″ broad jump. His workout-warrior NFL Combine performance alone will get the 6-foot, 221-pounder easily drafted with his size/speed profile.

Diving deeper into Guerendo's profile, it's not surprising he was so under the radar even though he was invited to test at the combine.

He never got the opportunity to break out at Wisconsin, sitting behind fellow draft-eligible running back Braelon Allen. His 9% career dominator rating pales in comparison to almost every other RB in the class. His final and lone season at Louisville, however, paints the picture of an RB who might be able to make some noise. He posted a 19% dominator rating with 11 TDs while catching 22 of his 24 targets for 234 yards (10.6 yards per reception). He split touches with incumbent starter Jawhar Jordan at Louisville. But Guerendo was more efficient on fewer carries forcing nearly the same amount of missed tackles despite 50 fewer carries than Jordan. His yards after contact per attempt ranked inside the top 20 in the nation in 2023 and the seventh-best in the class.

The 49ers traded up to draft the super athletic Isaac Guerendo in the 4th round. I'd like to think that Elijah Mitchell is dialed in as CMC's handcuff, but Guerendo's addition creates some doubt.

Player News
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Isaac Guerendo selected No. 129 by San Francisco 49ers

The San Francisco 49ers have selected RB Isaac Guerendo with the 129th pick in the 2024 NFL Draft.

Fantasy Impact

Guerendo is a physical runner that broke out his last year at Wisconsin. Unfortunately, it looks like he won't get much work behind superstar Christian McCaffrey. He may receive some work in blowout games, but otherwise assumes to be buried in the depth chart for the 2024 season.

Emily Maingi11 weeks ago
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Image of FantasyPros Staff by FantasyPros Staff in FantasyJul 11, 2024
ECRBestWorst# of Experts
DraftRB #84RB #65RB #11653
Dynasty ----
Running Backs#68
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Projections (2024)
Rush AttRush YdsRush TdsRecsRec YdsRec TdsFumblesPoints
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Statistics (avgs.)
Rush YdsRush TdsRecsPoints
Player stats are not available for the 2023 season
Game Log
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Game Log
OPPRush YdsRush TdsRecsPoints
Player does not have any game data for the 2023 season
Strength of Schedule
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Strength of Schedule (2024)
Next Gamevs. NYJ7th easiest opponent
Next 3 GamesMIN, LAR, NE31st easiest opponents
Playoffs (?)LAR, MIA, DET32nd easiest opponents
Rest of Season--26th easiest remaining opponents