| # | Player | Pos | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | AVG | TTL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Christian McCaffrey | RB | SF | 41.7 | 17.7 | - | 23.5 | 34.6 | 20.1 | 27.5 | 137.6 | |||||||||||
| 2 | Aaron Jones Sr. | RB | MIN | 42.2 | 4 | 14.3 | 34.6 | 2.9 | 27.3 | 20.9 | 125.3 | |||||||||||
| 3 | Dalvin Cook | RB | FA | 19.8 | 11.4 | 26.9 | 23.1 | 11.6 | 24.3 | 19.5 | 117.1 | |||||||||||
| 4 | Derrick Henry | RB | BAL | 13.8 | 3.3 | 16.8 | 6.3 | 21.9 | 31.1 | 15.5 | 93.2 | |||||||||||
| 5 | Chris Carson | RB | FA | 18.3 | 21.9 | 7.4 | 15 | 11.3 | 16.1 | 15 | 90 | |||||||||||
| 6 | Josh Jacobs | RB | GB | 26.3 | - | 13.4 | 8.1 | 24 | 16.1 | 17.6 | 87.9 | |||||||||||
| 7 | Tevin Coleman | RB | FA | 15.7 | 12.1 | 6.1 | 35.8 | 3.6 | 7.2 | 13.4 | 80.5 | |||||||||||
| 8 | Ezekiel Elliott | RB | FA | 15.1 | 21.3 | 20.7 | - | 13.9 | 6.3 | 15.5 | 77.3 |