| # | Player | Pos | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | AVG | TTL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jonathan Taylor | RB | IND | 9.6 | 28.6 | 19.7 | 31.2 | 35.4 | 5.7 | 46.6 | BYE | 6.6 | 12.1 | 11.4 | 20.7 | 206.9 | |||||||
| 2 | Jahmyr Gibbs | RB | DET | 15.7 | 14.7 | 6.5 | 33.8 | BYE | 2.8 | 35.2 | 14.6 | 44.4 | 8.6 | 30 | 20.6 | 206.3 | |||||||
| 3 | Christian McCaffrey | RB | SF | 20.1 | 19.9 | 17.1 | 32.1 | 6.8 | 29.3 | 9.6 | 30.1 | 20.2 | 13.4 | BYE | 19.9 | 198.6 | |||||||
| 4 | De'Von Achane | RB | MIA | 16.1 | 10.6 | 27 | 9.8 | 15.1 | 10.6 | 34.5 | 16.5 | BYE | 19.4 | 16.5 | 17.6 | 176.1 | |||||||
| 5 | Bijan Robinson | RB | ATL | 24.1 | BYE | 29.8 | 15.2 | 2.8 | 9.6 | 8.8 | 26.3 | 12.7 | 25.3 | 7.4 | 16.2 | 162 | |||||||
| 6 | James Cook III | RB | BUF | 19.5 | 4.9 | 8.7 | BYE | 33.6 | 12.5 | 5.7 | 17.4 | 18.9 | 15.7 | 9.1 | 14.6 | 146 | |||||||
| 7 | Josh Jacobs | RB | GB | 27.7 | BYE | 27 | 17.8 | 10.5 | 16 | 14.7 | 4 | - | 9.1 | 15.2 | 15.8 | 142 | |||||||
| 8 | Rico Dowdle | RB | CAR | 3 | 29.4 | 29.9 | 9.6 | 5.4 | 26.1 | 12.3 | 10 | 7.4 | 7.9 | BYE | 14.1 | 141 |