Tonight’s MLB DFS main slate starts at 7:07 p.m. ET at DraftKings and FanDuel and has 12 games. The suggested pick ’em choices from Underdog are also from the 12-game slate.
Check out our best picks on the MLB Underdog Cheat Sheet 
Today’s MLB DFS & Player Props Picks
Friday’s Starting Pitcher Rankings
Framber Valdez is a beast at home. According to FanGraphs, in 167 innings at home since last year, Valdez has spun a 2.16 ERA and 2.78 xFIP with a 1.05 WHIP, 7.8 BB% and 26.9 K%. Valdez has a dreamy combo of a tasty matchup and more delectable betting info tonight.
The Orioles are 21st in wRC+ (85) with a 23.9 K% versus lefties and 28th in wRC+ (80) with a 24.0 K% on the road in 2025. Thus, the Astros are listed as commanding -235 favorites, and the game’s total is 8.0 runs.
Chris Bassitt’s 4.39 ERA in his previous five starts spanning 26.2 innings was notably worse than his 3.69 xFIP and 3.80 SIERA. Additionally, like Valdez, Bassitt is outstanding at home, albeit not as impressive as the aforementioned southpaw. Bassitt has tallied a 3.69 ERA, 3.67 xFIP, 1.35 WHIP, 7.9 BB% and 24.3 K% in 178 innings at home since last year. He can please the home crowd tonight in a plus matchup.
The Rangers are tied for 25th in wRC+ (93) with a 21.5 K% versus righties and tied for 22nd in wRC+ (92) with a 22.1 K% on the road this year. In addition, Texas was dead last in wRC+ (85) with a 23.2 K% in the previous 30 days. The Blue Jays are slight underdogs (EVEN), but the game’s total is a pitcher-friendly 7.5 runs.
Sean Manaea is another pitcher who’s excelled at home, making it a hat trick. In 108.1 innings at home since last season, Manaea has recorded a 3.82 ERA, 3.51 xFIP, 0.98 WHIP, 7.0 BB% and 27.6 K%. I ranked the lefty behind Bassitt because he has a more challenging matchup.
The Mariners are 10th in wRC+ (103) with a 24.9 K% versus lefties and tied for second in wRC+ (113) with a 21.6 K% on the road this season. Yet, Seattle is tied for 25th in wRC+ (91) with a 25.2 K% in the previous 30 days. Finally, the Mets are -120 favorites, and the game’s total is 8.5 runs.
Suggested Lineup Stacks
Coors Field and another launching pad are hosting contests tonight. However, gamers shouldn’t sleep on Fenway Park. Ol’ reliable is tied for the fourth-highest park factor for runs (1.093). The Red Sox also have a cushy matchup against Sandy Alcantara tonight. Miami’s righty has a 6.55 ERA, 5.19 xERA, 4.54 xFIP, 4.75 SIERA and 1.45 WHIP this season. He’s also ceded a .326 wOBA to 263 left-handed batters and a .346 wOBA to 273 right-handed batters this year. Boston’s hitters should tee off on him tonight.
Sutter Health Park was the ballpark I not-so-subtly teased above. According to Baseball Savant, the Athletics’ temporary home has the second-highest park factor for runs (119) and a park factor of 111 for homers. The Angels will get a lift in the road contest. Jack Perkins isn’t an imposing matchup, either. The rookie righty has a 4.08 ERA, 4.21 xFIP and 3.83 SIERA in 10 appearances (two starts) this season. Moreover, he has a 7.15 ERA and 4.45 xFIP in 11.1 innings at home this year. Finally, the relievers for the A’s have the third-highest bullpen ERA (5.07) in 2025.
Core Studs
- Geraldo Perdomo is having a breakout season at the dish, with 13 homers, 72 runs, 79 RBIs, 19 stolen bases, a .388 OBP, .15 ISO, .364 wOBA, .355 xwOBA and 134 wRC+ in 537 plate appearances.
- Yoan Moncada has whacked eight homers with a .344 OBP, .236 ISO, .359 wOBA and 130 wRC+ in 160 plate appearances against righties this season.
- Roman Anthony is in a groove, hitting two homers with 14 runs, 10 RBIs, one stolen base, a .434 OBP, .188 ISO, .404 wOBA and 158 wRC+ in his previous 99 plate appearances.
Value Plays/Punts
- Masataka Yoshida has recorded a .347 OBP, .161 ISO, .348 wOBA and 120 wRC+ against righties since 2023.
- The light bulb hasn’t come on yet for Tyler Locklear in his limited time in the Majors. Still, he hit 19 homers with 70 runs, 82 RBIs, 18 stolen bases, a .401 OBP, .225 ISO, .411 wOBA and 136 wRC+ in 434 plate appearances in Triple-A this year, and he’ll get a boost from tonight’s park factors and pitching matchup.
- Luis Rengifo has hit three homers with 16 runs, eight RBIs, two stolen bases, a .363 OBP, .160 ISO, .356 wOBA and 128 wRC+ in his previous 91 plate appearances.
Friday’s Top 3 Underdog Player Props
Check out our best picks on the MLB Underdog Cheat Sheet
Roman Anthony (OF, DH – BOS): 8.5 Fantasy Points – Higher
Anthony has excelled with the platoon advantage this year. The left-handed-hitting rookie has hit one homer with a .424 OBP, .157 ISO, .384 wOBA and 144 wRC+ in 151 plate appearances against righties this season.
Geraldo Perdomo (SS – ARI): 9.5 Fantasy Points – Higher
Perdomo is on fire. In his previous 110 plate appearances, he’s rattled off three homers, 19 runs, 14 RBIs, six stolen bases, a .459 OBP, .183 ISO, .438 wOBA and 185 wRC+.
Yoan Moncada (3B – LAA): 1.5 Hits + Runs + RBIs – Higher
Moncada has turned back the clock this year. In 53 games and 183 plate appearances, he has tallied 20 singles, eight doubles, one triple, eight homers, 26 runs, 27 RBIs, a .233 batting average, .228 xBA, .447 SLG and .441 xSLG. Meanwhile, Perkins has yielded a .280 batting average, .321 OBP, .520 SLG and .353 wOBA to 28 left-handed batters faced at Sutter Health Park.
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Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.
