Tonight’s MLB DFS main slate starts at 7:05 p.m. ET at DraftKings and FanDuel and has 11 games. The suggested pick ’em choices from Underdog are also from the 11-game slate.
Check out our best picks on the MLB Underdog Cheat Sheet 

Today’s MLB DFS & Player Props Picks
Friday’s Starting Pitcher Rankings
Cristopher Sanchez has pitched well lately, with room for better results tonight if he pitches closer to his peripherals. According to FanGraphs, Sanchez has the following statistics in his previous five starts spanning 30.2 innings.
- 3.82 ERA
- 2.73 xFIP
- 3.09 SIERA
- 1.34 WHIP
- One win
- Four quality starts
- 51.1 GB%
- 5.3 BB%
- 27.5 K%
- 12.6 SwStr%
- 29.9 CSW%
- 114 stuff+
- 107 location+
- 124 pitching+
Sanchez has a golden opportunity to pitch to his ceiling tonight in a delectable matchup.
The Marlins are 28th in wRC+ (76) with a 21.5 K% versus lefties and 26th in wRC+ (89) with a 21.3 K% at home in 2025. Miami was also 26th in wRC+ (89) with a 20.2 K% in the previous 30 days. So, the Phillies are commanding -260 favorites, and the game’s total is a pitcher-friendly 7.5 runs.
Rookie lefty Ian Seymour had a 2.62 ERA, 3.81 xFIP, 1.14 WHIP, 5.6 BB%, 29.2 K%, 14.9 SwStr% and 28.4 CSW% in 16 appearances (15 starts) in Triple-A this year, totaling 86 innings. He’s also done well in 14 appearances (two starts) lasting 33.1 innings for the Rays, recording the following statistics.
- 2.97 ERA
- 2.73 xERA
- 3.04 xFIP
- 2.87 SIERA
- 1.02 WHIP
- 14.1 SwStr%
- 30.7 CSW%
Interestingly, while the assumption might be that Seymour inflated his numbers with his bullpen work, the following are his stats in two starts spanning 10 innings.
- 0.90 ERA
- 1.61 xFIP
- 1.91 SIERA
- 0.70 WHIP
- 5.3 BB%
- 42.1 K%
- 16.8 SwStr%
- 34.9 CSW%
- 102 stuff+
- 107 location+
- 108 pitching+
Seymour has a mouthwatering matchup and rock-solid betting info tonight.
The Guardians are tied for 25th in wRC+ (78) with a 23.1 K% versus lefties and 28th in wRC+ (81) with a 21.6 K% on the road this year. Cleveland was also dead last in wRC+ (65) with a 24.1 K% in the previous 30 days. Thus, the Rays are -135 favorites, and the game’s total is 8.0 runs.
Cam Schlittler has a treacherous matchup. The Blue Jays are in the top five in wRC+ versus righties, on the road and in the previous 30 days. Therefore, Schlittler is strictly a GPP suggestion. However, he’s pitched well enough to warrant GPP consideration.
In his last five starts spanning 28.2 innings, the rookie righty has had the following stats.
- 1.26 ERA
- 3.17 xFIP
- 3.29 SIERA
- 0.94 WHIP
- One win
- Three quality starts
- 8.1 BB%
- 29.7 K%
- 12.7 SwStr%
- 27.8 CSW%
- 114 stuff+
- 101 location+
- 111 pitching+
In addition to Schlitter’s sterling numbers making him an intriguing tournament pick, his betting info is also desirable. The Yankees are listed as -140 favorites, and the game’s total is 8.5 runs.

Suggested Lineup Stacks
- Road (Coors Field)
- Game Total/Moneyline: Unlisted/Unlisted
The most significant risk for stacking the Padres against Kyle Freeland is that he throws a temper tantrum and gets members of the Friars ejected. Joking aside, Freeland isn’t a big-league caliber starter, and the Rockies are an unserious organization. The veteran lefty has a 6.00 ERA, 4.88 xFIP, 4.49 SIERA and 1.59 WHIP in his previous six starts. Freeland has also coughed up a .394 wOBA to 52 left-handed batters at home and a .405 wOBA to 202 right-handed batters at Coors Field. Finally, Colorado’s relievers have the second-highest ERA (5.30) in 2025.
Tyler Glasnow hasn’t been in his best form lately, and the hitter-friendly renovated Oriole Park at Camden Yards isn’t an ideal venue for him to turn around his fortunes. Glasnow has a 4.15 ERA, 3.92 xFIP, 3.77 SIERA and 10.2 BB% in his previous four starts. Glasnow isn’t a cushy matchup for the Orioles, but the hosts can get the better of Glasnow if his shaky control fails him tonight. In addition, the Dodgers have a slightly below-average bullpen, with the 11th-highest ERA this season.
Core Studs
- Manny Machado has launched 25 long-balls with a .349 OBP, .221 ISO, .359 wOBA and 133 wRC+ in 464 plate appearances against southpaws since 2023.
- Fernando Tatis is in good form, rattling off two homers, 16 runs, 14 RBIs, five stolen bases, a .370 OBP, .140 ISO, .341 wOBA, .354 xwOBA and 122 wRC+ in his previous 119 plate appearances.
- Gunnar Henderson has ripped nine homers with a .401 OBP, .283 ISO, .432 wOBA and 181 wRC+ in 182 plate appearances against righties at home this season.
Value Plays/Punts
- Jeremiah Jackson has hit four homers with 15 runs, 17 RBIs, a .357 OBP, .223 ISO, .388 wOBA, .322 xwOBA and 151 wRC+ in his previous 98 plate appearances.
- Dylan Beavers has hit one homer with a .469 OBP, .146 ISO, .430 wOBA and 180 wRC+ in 49 plate appearances against righties in his rookie season.
- Dalton Rushing is a DraftKings-specific punt at catcher. He’s struggled with inconsistent playing time in the Majors. However, Rushing hit five homers with a .424 OBP, .206 ISO, .414 wOBA and 139 wRC+ in 132 plate appearances in Triple-A this year.

Friday’s Top 3 Underdog Player Props
Check out our best picks on the MLB Underdog Cheat Sheet 
Gunnar Henderson (SS, DH – BAL): 7.5 Fantasy Points – Higher
Even before the Orioles renovated their ballpark to make it more hitter-friendly, Henderson enjoyed hitting with the platoon advantage at home. He hit 18 homers with a .369 OBP, .283 ISO, .407 wOBA and 171 wRC+ in 255 plate appearances against righties at home. So, he should clear the low bar of 7.5 fantasy points tonight, even in a potentially challenging matchup.
Manny Machado (3B, DH – SD): 8.5 Fantasy Points – Higher
In addition to Machado’s excellent numbers against lefties since 2023 above, he’s also having a superb season at the plate. In 598 plate appearances this year, Machado has recorded 22 homers, 80 runs, 81 RBIs, 12 stolen bases, a .344 OBP, .181 ISO, .348 wOBA, .372 xwOBA and 127 wRC+.
Fernando Tatis (OF – SD): 9.5 Fantasy Points – Higher
Tatis isn’t a world-beater against lefties. Still, he’s blasted 12 bombs with a .363 OBP, .149 ISO, .333 wOBA and 115 wRC+ in 430 plate appearances against southpaws since 2023.

Subscribe: YouTube | Spotify | Apple Podcasts | iHeart | Castbox | Amazon Music | Podcast Addict | SoundCloud | TuneIn
Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.