Wednesday’s MLB DFS main slates at DraftKings and FanDuel start at 7:07 p.m. ET, and they feature 10 games. The Underdog pick’em plays are also from those 10 games.
Wednesday’s Top MLB DFS Picks & Player Props
Wednesday’s Starting Pitcher Rankings (5/13)
Jacob Misiorowski is a strikeout machine. According to FanGraphs, Misiorowski’s 39.5% strikeout rate is the highest among qualified pitchers, and it’s supported by the highest swinging-strike rate (17.1%), the highest called-plus-swinging strike rate (34%) and the highest stuff+ (125).
He’s more than just a gaudy strikeout rate, too. Misiorowski has the following numbers in eight starts spanning 44 innings this season:
- 3 wins
- 3 quality starts
- 2.45 ERA
- 2.72 xERA
- 2.39 xFIP
- 2.40 SIERA
- 0.95 WHIP
- 9.6% walk rate
- 39.5% strikeout rate
- 17.1% SwStr%
- 34% CSW%
- 125 stuff+
- 96 location+
- 119 pitching+
The flamethrowing righty has a desirable matchup and rock-solid betting info. The Padres are tied for 23rd in wRC+ (94) with a 22.7% strikeout rate versus righties and tied for 18th in wRC+ (89) with a 23.9% strikeout rate on the road in 2026.
Thus, the Brewers are -134 favorites, and the game’s total is a pitcher-friendly seven runs.
Among 132 pitchers with at least 30 innings this year, Shohei Ohtani is first in ERA (0.97), second in xERA (2.18), tied for 17th in xFIP (3.11), tied for second in WHIP (0.81) and 14th in strikeout rate (29%).
Ohtani has also logged two wins, six quality starts, a 14.1% SwStr%, 31.5% CSW%, 114 stuff+, 101 location+ and 114 pitching+. Ohtani has a valid case for being the top pitcher on this slate, and his ranking is more representative of how good Jacob Misiorowski has been than a knock on Ohtani.
Ohtani has a plus-matchup and tasty betting info. The Giants are 27th in wRC+ (87) with a 20.9% strikeout rate versus righties and tied for 22nd in wRC+ (84) with a 22.2% strikeout rate on the road. The Dodgers are -250 favorites, and the game’s total is eight runs.
Ohtani has a massive ceiling, and the two forthcoming stacks even open the door to using Misiorowski and Ohtani together.
Max Meyer is excelling this year, albeit with some luck relative to his ERA estimators. In eight starts, totaling 42 innings, Meyer has amassed the following stats:
- 3 wins
- 1 quality start
- 2.79 ERA
- 4.03 xERA
- 3.60 xFIP
- 3.63 SIERA
- 1.10 WHIP
- 8.5 BB%
- 25.6 K%
- 13.5 SwStr%
- 29.1 CSW%
- 96 stuff+
- 110 location+
- 107 pitching+
Meyer has a middle-of-the-pack matchup and adequate betting info. The Twins are tied for 16th in wRC+ (100) with a 23.4% strikeout rate versus righties and 16th in wRC+ (104) with a 20.8% strikeout rate at home this season.
Finally, the Marlins are -125 favorites, and the game’s total is 8.5 runs. Meyer is a better option as an SP2 in all game types on DraftKings than as an option in any game types at FanDuel.
Suggested Lineup Stacks
Simeon Woods Richardson has the second-highest ERA (6.92), the highest xERA (5.74), the highest xFIP (5.76), the highest SIERA (5.69), the highest WHIP (1.72), the third-highest home runs allowed per nine innings (1.85) and the lowest strikeout rate (10.6%) among tonight’s probable starting pitchers.
Furthermore, Woods Richardson has allowed a .324 wOBA to lefties and a .346 wOBA to righties since last year. He’s an ideal matchup for Miami’s offense. Among the eight projected starters with over 120 plate appearances against righties since 2024, five have posted at least a 108 wRC+, with three posting at least a 121 wRC+. They have some firepower.
The White Sox don’t have an obviously easy matchup tonight. Seth Lugo‘s 3.21 ERA in eight starts isn’t outrageously out of whack with his 3.90 xFIP, but it’s quite a bit lower than his 4.15 SIERA and 4.46 xERA.
The primary reason for suggesting the White Sox as a stack against Lugo is his struggles against lefties. Lugo has allowed a .356 wOBA to 490 left-handed batters since last year. Meanwhile, Chicago’s lineup features three left-handed batters in the top four spots in their order and seven players who are left-handed or switch-hitters.
Chicago can tee off on Lugo, and they’re an affordable stack, even with their high-salaried slugging first baseman.
Core Studs
- Munetaka Murakami has hit 11 homers with a .367 on-base percentage (OBP), .333 ISO, .397 wOBA and 153 wRC+ in 120 plate appearances against righties this season.
- Liam Hicks is off to a torrid start this season. Through 142 plate appearances, he’s rattled off nine homers, 20 runs, 35 RBIs, one stolen base, a .359 OBP, .242 ISO, .386 wOBA and 146 wRC+.
- Colson Montgomery has hit 23 homers with a .321 OBP, .295 ISO, .360 wOBA and 131 wRC+ in 316 plate appearances against righties since 2024.
Value Plays/Punts
- Rookie Sam Antonacci is a sparkplug atop Chicago’s order, with one homer, 13 runs, nine RBI, a .382 OBP, .133 ISO, .361 wOBA and 128 wRC+ in 91 plate appearances this season.
- Xavier Edwards has tallied six homers, a .384 OBP, .099 ISO, .353 wOBA and 125 wRC+ in 759 plate appearances against righties since 2024.
- Colt Keith offers gamers plenty of bang for their buck at his tiny salary, with a .332 wOBA and 109 wRC+ in 122 plate appearances this year.
Wednesday’s Top 3 Underdog Player Props
Check out our best picks on the MLB Underdog Cheat Sheet 
Xavier Edwards is a productive hitter atop Miami’s lineup.
Edwards has amassed 48 hits (35 singles, seven doubles, two triples and four homers) with 27 runs, 14 RBIs, a .314 batting average, .400 OBP, .150 ISO, .386 wOBA and 146 wRC+ in 42 games and 176 plate appearances this season.
The switch-hitter has surpassed 1.5 combined hits + runs + RBIs in three of his last four starts and seven of his last 11.
Kyle Stowers (OF – MIA): 1.5 Hits + Runs + RBIs — Higher (0.84x Payout)
Kyle Stowers is a handful for righties. In 579 plate appearances against right-handed pitching since 2024, he’s tallied 137 hits (78 singles, 28 doubles, three triples and 28 homers) with a .269 batting average, .348 OBP, .231 ISO, .362 wOBA and 133 wRC+.
Even in an underwhelming season at the dish to this point, Stowers has 17 hits, 10 runs and three RBI in 20 games (19 starts) and 82 plate appearances.
Michael King has a pristine 2.76 ERA in eight starts. However, his 3.76 xERA, 4.11 xFIP and 4.03 SIERA are all less impressive than his ERA.
Even while outkicking his ERA estimators, King has allowed over 1.5 earned runs in half of his starts. While he’s outperformed his peripheral numbers, King should allow more than 1.5 earned runs tonight.
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Josh Shepardson is a featured writer at FantasyPros. For more from Josh, check out his archive and follow him @BChad50.
