| Player | BYE | TACKLE | ASSIST | SACK | PD | INT | FF | FR | TD | FPTS |
|---|---|---|---|---|---|---|---|---|---|---|
| Jordyn Brooks MIA | 6 | 135.5 | 79.3 | 3.0 | 3.8 | 0.3 | 1.0 | 0.8 | 0.1 | 290.2 |
| Blake Cashman MIN | 6 | 128.1 | 77.6 | 3.4 | 3.6 | 0.3 | 1.1 | 0.9 | 0.1 | 279.5 |
| Jack Campbell DET | 6 | 118.4 | 73.0 | 2.9 | 4.1 | 0.8 | 2.2 | 1.3 | 0.1 | 269.2 |
| T.J. Edwards CHI | 10 | 128.2 | 56.7 | 2.3 | 8.6 | 1.3 | 0.5 | 0.3 | 0.1 | 267.2 |
| Nick Bolton KC | 5 | 115.4 | 71.0 | 2.4 | 6.1 | 1.0 | 1.0 | 0.8 | 0.1 | 258.7 |
| Fred Warner SF | 8 | 114.4 | 57.4 | 1.4 | 7.5 | 1.3 | 2.9 | 1.7 | 0.1 | 257.4 |
| Carson Schwesinger CLE | 11 | 118.4 | 72.5 | 2.1 | 3.9 | 0.8 | 0.7 | 0.1 | 0.1 | 254.1 |
| Mack Wilson Sr. ARI | 14 | 115.6 | 51.1 | 1.2 | 10.8 | 1.6 | 1.7 | 1.1 | 0.1 | 252.7 |
| Foyesade Oluokun JAC | 7 | 107.8 | 65.0 | 2.1 | 8.0 | 1.2 | 1.3 | 1.1 | 0.1 | 247.2 |
| Cedric Gray TEN | 9 | 117.7 | 65.0 | 1.4 | 3.8 | 0.3 | 0.7 | 0.6 | 0.1 | 244.0 |
PD = Passes Defended, FF = Forced Fumbles, FR = Fumbles Recovered, FPTS = Fantasy Points (based on Standard Scoring)
