Buffalo Sabres
Atlantic Division
| Date (ET) | Opponent |
|---|---|
| Thu Oct 1, 7:00pm | at. Columbus Blue Jackets |
| Sat Oct 3, 7:00pm | vs. Chicago Blackhawks |
| Tue Oct 6, 7:00pm | vs. Minnesota Wild |
| Thu Oct 8, 7:00pm | vs. Dallas Stars |
| Sat Oct 10, 7:00pm | vs. Utah Mammoth |
| Mon Oct 12, 1:00pm | vs. Florida Panthers |
| Tue Oct 13, 6:30pm | at. Montreal Canadiens |
| Thu Oct 15, 7:00pm | at. Toronto Maple Leafs |
| Sat Oct 17, 7:00pm | at. Montreal Canadiens |
| Wed Oct 21, 7:30pm | vs. Philadelphia Flyers |
| Sat Oct 24, 7:00pm | at. Washington Capitals |
| Tue Oct 27, 10:30pm | at. San Jose Sharks |
| Thu Oct 29, 10:00pm | at. Anaheim Ducks |
| Sat Oct 31, 4:00pm | at. Los Angeles Kings |
| Wed Nov 4, 7:30pm | vs. Ottawa Senators |
| Fri Nov 6, 7:00pm | vs. Columbus Blue Jackets |
| Sun Nov 8, 3:30pm | vs. Vegas Golden Knights |
| Wed Nov 11, 7:00pm | vs. Tampa Bay Lightning |
| Thu Nov 12, 8:00pm | at. Chicago Blackhawks |
| Sat Nov 14, 8:00pm | at. Dallas Stars |
| Tue Nov 17, 7:00pm | at. Philadelphia Flyers |
| Thu Nov 19, 7:00pm | at. Washington Capitals |
| Sat Nov 21, 6:00pm | at. Florida Panthers |
| Sun Nov 22, 5:00pm | at. Tampa Bay Lightning |
| Wed Nov 25, 7:00pm | vs. New York Rangers |
| Fri Nov 27, 8:00pm | vs. Pittsburgh Penguins |
| Tue Dec 1, 8:00pm | at. Edmonton Oilers |
| Thu Dec 3, 8:00pm | at. Calgary Flames |
| Fri Dec 4, 9:00pm | at. Vancouver Canucks |
| Sun Dec 6, 8:00pm | at. Seattle Kraken |
| Thu Dec 10, 7:00pm | vs. Edmonton Oilers |
| Sat Dec 12, 7:00pm | vs. Anaheim Ducks |
| Mon Dec 14, 2:00pm | at. Ottawa Senators |
| Tue Dec 15, 7:00pm | vs. Calgary Flames |
| Fri Dec 18, 7:30pm | vs. Montreal Canadiens |
| Sun Dec 20, 6:00pm | vs. Los Angeles Kings |
| Tue Dec 22, 7:00pm | at. Pittsburgh Penguins |
| Sat Dec 26, 7:00pm | vs. New Jersey Devils |
| Mon Dec 28, 7:00pm | vs. Detroit Red Wings |
| Wed Dec 30, 7:00pm | at. Florida Panthers |
| Sat Jan 2, 7:00pm | at. Tampa Bay Lightning |
| Mon Jan 4, 7:30pm | vs. Winnipeg Jets |
| Date (ET) | Opponent | |
|---|---|---|
| Tue Jan 5, 7:30pm | at. Boston Bruins | |
| Fri Jan 8, 7:00pm | at. Columbus Blue Jackets | |
| Sat Jan 9, 7:00pm | vs. Carolina Hurricanes | |
| Tue Jan 12, 7:00pm | vs. New Jersey Devils | |
| Thu Jan 14, 7:30pm | vs. Colorado Avalanche | |
| Sat Jan 16, 7:00pm | vs. Nashville Predators | |
| Mon Jan 18, 2:00pm | vs. Montreal Canadiens | |
| Wed Jan 20, 7:00pm | at. New York Islanders | |
| Thu Jan 21, 7:00pm | vs. Seattle Kraken | |
| Sun Jan 24, 3:00pm | at. Winnipeg Jets | |
| Wed Jan 27, 9:00pm | at. Utah Mammoth | |
| Thu Jan 28, 10:00pm | at. Vegas Golden Knights | |
| Sat Jan 30, 5:00pm | at. Colorado Avalanche | |
| Wed Feb 3, 7:00pm | vs. New York Islanders | |
| Sat Feb 6, 8:00pm | NHL All-Star Game | |
| Sat Feb 13, 7:00pm | at. Carolina Hurricanes | |
| Mon Feb 15, 6:00pm | at. New York Rangers | |
| Thu Feb 18, 7:00pm | vs. Carolina Hurricanes | |
| Sat Feb 20, 1:30pm | at. New Jersey Devils | |
| Sun Feb 21, 3:30pm | at. Detroit Red Wings | |
| Wed Feb 24, 7:00pm | at. Philadelphia Flyers | |
| Fri Feb 26, 7:30pm | vs. Ottawa Senators | |
| Sat Feb 27, 7:00pm | vs. Toronto Maple Leafs | |
| Tue Mar 2, 7:00pm | vs. Pittsburgh Penguins | |
| Thu Mar 4, 7:00pm | vs. St. Louis Blues | |
| Sat Mar 6, 3:00pm | vs. New York Rangers | |
| Sun Mar 7, 3:00pm | at. Ottawa Senators | |
| Tue Mar 9, 7:00pm | vs. Vancouver Canucks | |
| Fri Mar 12, 7:00pm | at. Detroit Red Wings | |
| Sun Mar 14, 7:00pm | at. Minnesota Wild | |
| Mon Mar 15, 7:00pm | vs. San Jose Sharks | |
| Thu Mar 18, 7:30pm | vs. Washington Capitals | |
| Sat Mar 20, 1:00pm | vs. Florida Panthers | |
| Sun Mar 21, 3:00pm | at. New York Islanders | |
| Tue Mar 23, 7:00pm | at. Boston Bruins | |
| Thu Mar 25, 7:00pm | vs. Toronto Maple Leafs | |
| Sun Mar 28, 8:30pm | at. St. Louis Blues | |
| Tue Mar 30, 8:00pm | at. Nashville Predators | |
| Thu Apr 1, 7:00pm | vs. Boston Bruins | |
| Sat Apr 3, 7:00pm | at. Toronto Maple Leafs | |
| Mon Apr 5, 7:00pm | vs. Tampa Bay Lightning | |
| Wed Apr 7, 7:30pm | vs. Boston Bruins | |
| Sat Apr 10, 6:00pm | vs. Detroit Red Wings | |
