Buffalo Sabres
Atlantic Division
| Date (ET) | Opponent |
|---|---|
| Thu Oct 12, 7:00pm | vs. New York Rangers |
| Sat Oct 14, 7:30pm | at. New York Islanders |
| Tue Oct 17, 7:30pm | vs. Tampa Bay Lightning |
| Thu Oct 19, 7:00pm | vs. Calgary Flames |
| Sat Oct 21, 7:00pm | vs. New York Islanders |
| Mon Oct 23, 7:00pm | vs. Montreal Canadiens |
| Tue Oct 24, 6:45pm | at. Ottawa Senators |
| Fri Oct 27, 7:00pm | at. New Jersey Devils |
| Sun Oct 29, 1:00pm | vs. Colorado Avalanche |
| Wed Nov 1, 7:00pm | at. Philadelphia Flyers |
| Fri Nov 3, 7:00pm | vs. Philadelphia Flyers |
| Sat Nov 4, 7:00pm | at. Toronto Maple Leafs |
| Tue Nov 7, 7:00pm | at. Carolina Hurricanes |
| Fri Nov 10, 7:00pm | vs. Minnesota Wild |
| Sat Nov 11, 7:30pm | at. Pittsburgh Penguins |
| Tue Nov 14, 7:00pm | vs. Boston Bruins |
| Fri Nov 17, 8:00pm | at. Winnipeg Jets |
| Sun Nov 19, 7:00pm | at. Chicago Blackhawks |
| Wed Nov 22, 7:00pm | at. Washington Capitals |
| Fri Nov 24, 6:00pm | vs. Pittsburgh Penguins |
| Sat Nov 25, 7:00pm | at. New Jersey Devils |
| Mon Nov 27, 7:00pm | at. New York Rangers |
| Thu Nov 30, 8:00pm | at. St. Louis Blues |
| Sat Dec 2, 7:00pm | at. Carolina Hurricanes |
| Sun Dec 3, 7:00pm | vs. Nashville Predators |
| Tue Dec 5, 7:30pm | vs. Detroit Red Wings |
| Thu Dec 7, 7:00pm | at. Boston Bruins |
| Sat Dec 9, 7:00pm | vs. Montreal Canadiens |
| Mon Dec 11, 7:00pm | vs. Arizona Coyotes |
| Wed Dec 13, 10:00pm | at. Colorado Avalanche |
| Fri Dec 15, 10:00pm | at. Vegas Golden Knights |
| Sat Dec 16, 9:00pm | at. Arizona Coyotes |
| Tue Dec 19, 7:00pm | vs. Columbus Blue Jackets |
| Thu Dec 21, 7:00pm | vs. Toronto Maple Leafs |
| Sat Dec 23, 7:30pm | at. New York Rangers |
| Wed Dec 27, 7:30pm | vs. Boston Bruins |
| Sat Dec 30, 5:00pm | vs. Columbus Blue Jackets |
| Sun Dec 31, 6:00pm | at. Ottawa Senators |
| Thu Jan 4, 7:00pm | at. Montreal Canadiens |
| Sat Jan 6, 7:00pm | at. Pittsburgh Penguins |
| Tue Jan 9, 7:00pm | vs. Seattle Kraken |
| Thu Jan 11, 7:00pm | vs. Ottawa Senators |
| Date (ET) | Opponent | |
|---|---|---|
| Sat Jan 13, 4:00pm | vs. Vancouver Canucks | |
| Mon Jan 15, 12:00pm | vs. San Jose Sharks | |
| Thu Jan 18, 7:00pm | vs. Chicago Blackhawks | |
| Sat Jan 20, 12:30pm | vs. Tampa Bay Lightning | |
| Tue Jan 23, 10:00pm | at. Anaheim Ducks | |
| Wed Jan 24, 10:30pm | at. Los Angeles Kings | |
| Sat Jan 27, 4:00pm | at. San Jose Sharks | |
| Sat Feb 3, 8:00pm | NHL All-Star Game | |
| Tue Feb 6, 7:00pm | vs. Dallas Stars | |
| Sat Feb 10, 1:00pm | vs. St. Louis Blues | |
| Tue Feb 13, 7:00pm | vs. Los Angeles Kings | |
| Thu Feb 15, 7:00pm | vs. Florida Panthers | |
| Sat Feb 17, 5:00pm | at. Minnesota Wild | |
| Mon Feb 19, 12:30pm | vs. Anaheim Ducks | |
| Wed Feb 21, 7:00pm | at. Montreal Canadiens | |
| Fri Feb 23, 7:00pm | at. Columbus Blue Jackets | |
| Sun Feb 25, 6:00pm | vs. Carolina Hurricanes | |
| Tue Feb 27, 7:00pm | at. Florida Panthers | |
| Thu Feb 29, 7:00pm | at. Tampa Bay Lightning | |
| Sat Mar 2, 7:00pm | vs. Vegas Golden Knights | |
| Sun Mar 3, 7:00pm | vs. Winnipeg Jets | |
| Wed Mar 6, 7:00pm | at. Toronto Maple Leafs | |
| Thu Mar 7, 8:00pm | at. Nashville Predators | |
| Sat Mar 9, 12:30pm | vs. Edmonton Oilers | |
| Tue Mar 12, 7:00pm | vs. Detroit Red Wings | |
| Thu Mar 14, 7:00pm | vs. New York Islanders | |
| Sat Mar 16, 12:30pm | at. Detroit Red Wings | |
| Mon Mar 18, 10:00pm | at. Seattle Kraken | |
| Tue Mar 19, 10:00pm | at. Vancouver Canucks | |
| Thu Mar 21, 9:00pm | at. Edmonton Oilers | |
| Sun Mar 24, 9:00pm | at. Calgary Flames | |
| Wed Mar 27, 7:00pm | vs. Ottawa Senators | |
| Fri Mar 29, 7:00pm | vs. New Jersey Devils | |
| Sat Mar 30, 7:00pm | vs. Toronto Maple Leafs | |
| Tue Apr 2, 7:00pm | vs. Washington Capitals | |
| Fri Apr 5, 7:00pm | vs. Philadelphia Flyers | |
| Sun Apr 7, 1:00pm | at. Detroit Red Wings | |
| Tue Apr 9, 8:00pm | at. Dallas Stars | |
| Thu Apr 11, 7:00pm | vs. Washington Capitals | |
| Sat Apr 13, 5:00pm | at. Florida Panthers | |
| Mon Apr 15, 7:00pm | at. Tampa Bay Lightning | |
