| # | Player | Pos | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | AVG | TTL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Todd Gurley II | RB | FA | 22.2 | 30.8 | 22.1 | 23.6 | 31.3 | 35.5 | 28.6 | 30.5 | 28.1 | 224.6 | |||||||||
| 2 | Saquon Barkley | RB | PHI | 19.8 | 17.8 | 20.2 | 19 | 26.9 | 33.4 | 21.9 | 15.6 | 21.8 | 174.6 | |||||||||
| 3 | James Conner | RB | ARI | 31.4 | 17 | 12 | 7.9 | 32.5 | 26.9 | - | 35.7 | 23.3 | 163.4 | |||||||||
| 4 | Alvin Kamara | RB | NO | 38.6 | 14.9 | 26.5 | 38.6 | 5.4 | BYE | 14.5 | 23.1 | 23.1 | 161.6 | |||||||||
| 5 | Kareem Hunt | RB | KC | 4.9 | 14.5 | 16.4 | 25 | 15.9 | 27 | 34.6 | 17.1 | 19.4 | 155.4 | |||||||||
| 6 | Melvin Gordon III | RB | FA | 23.1 | 27.6 | 15.4 | 27.4 | 20 | 34 | - | - | 24.6 | 147.5 | |||||||||
| 7 | James White | RB | FA | 13.6 | 11.9 | 12.6 | 27.2 | 18.7 | 11.7 | 25.7 | 20.4 | 17.7 | 141.8 | |||||||||
| 8 | T.J. Yeldon | RB | FA | 14.4 | 8.1 | 12 | 21.5 | 22.2 | 8.5 | 15.3 | 12.5 | 14.3 | 114.5 |