| # | Player | Pos | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | AVG | TTL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Patrick Mahomes II | QB | KC | 28.3 | 38.8 | 25.3 | 22.9 | 15.8 | 27 | 32.8 | 26 | 26.8 | 27.1 | 243.7 | ||||||||
| 2 | Alvin Kamara | RB | NO | 43.1 | 17.9 | 34 | 41.1 | 6.9 | BYE | 15.5 | 26.6 | 33.6 | 27.3 | 218.7 | ||||||||
| 3 | Adam Thielen | WR | PIT | 16.2 | 31.1 | 24.5 | 27.5 | 24.6 | 29.3 | 26 | 22.8 | 12.7 | 23.9 | 214.7 | ||||||||
| 4 | James Conner | RB | ARI | 33.9 | 19.5 | 14.5 | 9.4 | 34.5 | 28.9 | - | 38.2 | 29.3 | 26 | 208.2 | ||||||||
| 5 | Saquon Barkley | RB | PHI | 20.8 | 24.8 | 22.7 | 22 | 28.9 | 37.9 | 26.4 | 20.1 | BYE | 25.5 | 203.6 | ||||||||
| 6 | Kareem Hunt | RB | KC | 4.9 | 15 | 16.4 | 26.5 | 16.4 | 29.5 | 37.1 | 19.6 | 33.1 | 22.1 | 198.5 | ||||||||
| 7 | Matt Ryan | QB | FA | 8.8 | 30.7 | 40.2 | 29.3 | 14.4 | 27.5 | 19.3 | - | 28 | 24.8 | 198.1 | ||||||||
| 8 | James White | RB | FA | 15.6 | 15.4 | 14.1 | 31.2 | 23.7 | 14.2 | 29.7 | 25.4 | 28.3 | 22 | 197.6 |