| Player | Team | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | TTL | AVG |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mike Davis | Multi | 40 | 15 | 1 | 0 | 4 | 0 | 0 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 79 | 6.6 |
| David Montgomery | CHI | 27 | 27 | 41 | 48 | 30 | bye | 30 | 59 | 32 | 34 | 35 | 47 | 39 | 45 | 36 | 35 | 49 | 614 | 38.4 |
| Cordarrelle Patterson | CHI | 20 | 15 | 9 | 7 | 2 | bye | 15 | 15 | 8 | 14 | 2 | 12 | 27 | 11 | 38 | 6 | 2 | 203 | 12.7 |
| Tarik Cohen | CHI | 51 | 22 | 32 | 28 | 29 | bye | 35 | 16 | 16 | 29 | 45 | 39 | 36 | 33 | 55 | 34 | 33 | 533 | 33.3 |
| Jamaal Williams | GB | 24 | 32 | 33 | 1 | 0 | 39 | 23 | 32 | 22 | 32 | bye | 38 | 27 | 25 | 24 | 21 | 0 | 373 | 26.6 |
| Aaron Jones Sr. | GB | 37 | 42 | 21 | 66 | 48 | 36 | 33 | 42 | 30 | 32 | bye | 41 | 38 | 35 | 35 | 52 | 75 | 663 | 41.4 |
| Dalvin Cook | MIN | 36 | 47 | 37 | 47 | 43 | 44 | 51 | 51 | 57 | 56 | 50 | bye | 24 | 33 | 28 | 0 | 0 | 604 | 43.1 |
| Alexander Mattison | MIN | 12 | 8 | 19 | 6 | 16 | 21 | 21 | 19 | 6 | 12 | 4 | bye | 26 | 27 | 0 | 0 | 0 | 197 | 15.2 |
| Ameer Abdullah | MIN | 4 | 7 | 1 | 7 | 10 | 6 | 1 | 3 | 8 | 5 | 8 | bye | 3 | 6 | 15 | 32 | 19 | 135 | 8.4 |
| Ito Smith | ATL | 38 | 23 | 3 | 30 | 34 | 18 | 3 | 0 | bye | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 149 | 21.3 |